5330417C22Rik Inhibitors
Elapor1 inhibitors are chemicals that can indirectly inhibit the function of the protein ELAPOR1 by targeting pathways and processes involved in autophagy and lysosomal functions. ELAPOR1 is implicated in the regulation of apoptosis and autophagy, particularly in the context of endosome-lysosome activities. Inhibitors such as Chloroquine and Bafilomycin A1 act by increasing lysosomal pH and inhibiting V-ATPase, respectively, which can affect the autophagic process and potentially the function of ELAPOR1 in this context.
Other inhibitors, like 3-Methyladenine, Wortmannin, LY294002, and SAR405, inhibit various PI3Ks which are crucial for the initiation and progression of autophagy, potentially altering ELAPOR1's involvement in these pathways. Compounds such as Spautin-1 and Vinblastine disrupt the formation and maturation of autophagosomes, a key step in autophagy where ELAPOR1 may have regulatory functions. E-64d and NH4Cl interfere with the degradation phase of autophagy, which can also indirectly affect ELAPOR1's role. MG-132 and Lys05 are examples of inhibitors that lead to the accumulation of autophagic substrates and increase lysosomal pH, respectively, which can further influence the functions associated with ELAPOR1 in the autophagy-lysosome pathway.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Lysosomotropic agent that can increase lysosomal pH and interfere with autophagic degradation, potentially affecting ELAPOR1's role in autophagy. | ||||||
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $96.00 $250.00 $750.00 $1428.00 | 280 | |
Specific V-ATPase inhibitor that can prevent acidification of lysosomes, thereby possibly influencing ELAPOR1 function in autophagy. | ||||||
Autophagy Inhibitor, 3-MA | 5142-23-4 | sc-205596 sc-205596A | 50 mg 500 mg | $56.00 $256.00 | 113 | |
Class III PI3K inhibitor that can inhibit the autophagy initiation process, possibly impacting ELAPOR1-mediated autophagy. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
PI3K inhibitor that can also inhibit autophagy at an early stage, possibly affecting ELAPOR1's regulatory role. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Another PI3K inhibitor that can inhibit autophagy by blocking the PI3K/AKT/mTOR pathway, potentially influencing ELAPOR1's function. | ||||||
Spautin-1 | 1262888-28-7 | sc-507306 | 10 mg | $165.00 | ||
Autophagy inhibitor that promotes the degradation of Vps34 PI3 kinase complexes, potentially impacting ELAPOR1-associated pathways. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $230.00 $450.00 $1715.00 $2900.00 | 4 | |
Microtubule-disrupting agent that can inhibit autophagosome maturation, possibly affecting ELAPOR1's function in autophagy. | ||||||
E-64 | 66701-25-5 | sc-201276 sc-201276A sc-201276B | 5 mg 25 mg 250 mg | $275.00 $928.00 $1543.00 | 14 | |
Lysosomal protease inhibitor that can block the final degradation of autophagic cargo, potentially influencing ELAPOR1's role in autophagy. | ||||||
Ammonium Chloride | 12125-02-9 | sc-202936 sc-202936A sc-202936B | 25 g 500 g 2.5 kg | $38.00 $54.00 $147.00 | 4 | |
Ammonium chloride acts as a weak base and can raise lysosomal pH, possibly affecting ELAPOR1's lysosomal function. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
Proteasome inhibitor that can lead to the accumulation of autophagic substrates, potentially impacting ELAPOR1's role in autophagic flux. | ||||||