RECK Activators encompass a diverse range of chemicals that, while not directly interacting with the RECK protein, influence its expression and activity through various indirect pathways. These activators function by modulating key cellular processes and signaling pathways that are intricately linked to the regulation of RECK. This regulation is crucial, as RECK plays a significant role in processes like matrix remodeling, inhibition of angiogenesis, and suppression of tumor invasion and metastasis.
The mechanisms by which these chemicals act are varied and complex, reflecting the multifaceted nature of cellular signaling. They include modulation of oxidative stress, inflammation, apoptosis, and various signaling pathways related to cancer and metabolism. For instance, some of these chemicals act by influencing transcription factors and enzymes that indirectly regulate RECK expression, such as those involved in inflammatory responses or cellular stress pathways. Others affect RECK through their role in modulating the activity of matrix metalloproteinases (MMPs), with which RECK has an inverse relationship.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A catechin in green tea, EGCG modulates angiogenesis and metastasis signaling pathways. It influences matrix metalloproteinases (MMPs), inversely regulated by RECK, and by modulating MMP activity, it can indirectly affect the stabilization of RECK expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A polyphenol from turmeric, Curcumin affects various signaling pathways, including those linked to inflammation and cancer. It modulates the activity of transcription factors and enzymes indirectly associated with RECK expression, such as NF-κB, which influences inflammatory responses and could impact RECK levels. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Found in grapes, Resveratrol influences sirtuins and other signaling molecules, affecting pathways related to aging and inflammation. This can indirectly impact RECK expression through modulation of cellular stress and inflammatory responses. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
A compound in cruciferous vegetables, Sulforaphane activates NRF2 and modulates inflammatory pathways. By influencing oxidative stress response and inflammation, it may indirectly impact RECK expression, as these factors are known to affect RECK levels. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
A flavonoid in many fruits and vegetables, Quercetin affects various signaling pathways, including those related to inflammation and apoptosis. Its role in modulating these pathways can indirectly influence RECK expression, particularly through its effects on cellular stress responses. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
An isoflavone in soy, Genistein affects multiple signaling pathways related to cell growth and angiogenesis. By influencing these pathways, it could indirectly modulate RECK expression, particularly in cancer-related signaling. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Known for its effects on cAMP signaling and phosphodiesterases, Caffeine could indirectly influence RECK expression by modulating cellular stress and energy metabolism pathways. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
The active component in chili peppers, Capsaicin influences signaling pathways related to pain and inflammation. By modulating these pathways, it could indirectly affect RECK expression, particularly in the context of inflammation and cellular stress responses. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
An alkaloid in certain plants, Berberine affects various signaling pathways, including those related to metabolism and inflammation. Its influence on these pathways could indirectly impact RECK expression, especially in metabolic and inflammatory contexts. | ||||||
Lycopene | 502-65-8 | sc-205738 sc-205738A sc-205738B | 1 mg 5 mg 1 g | $146.00 $582.00 $6248.00 | 4 | |
Found in tomatoes, Lycopene influences antioxidant response and cellular stress pathways. Its role in modulating oxidative stress can indirectly impact RECK expression, as oxidative stress affects various signaling pathways that could regulate RECK. | ||||||