Date published: 2026-7-12

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RANK Antibodies

Santa Cruz Biotechnology features a diverse variety of RANK Antibodies for investigating RANK protein activity in various biological processes. RANK Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA) applications.RANK, or Receptor Activator of Nuclear Factor kappa-B, functions as a crucial protein in regulating bone metabolism and immune responses. RANK signaling drives osteoclast differentiation and activation, maintaining essential bone homeostasis. Research has demonstrated RANK involvement in multiple pathological conditions, including osteoporosis and certain cancers, establishing RANK as a significant therapeutic target.Monoclonal RANK antibodies enable researchers to explore bone remodeling mechanisms through precise detection methods. Understanding RANK signaling pathways advances knowledge of skeletal development and bone diseases. Investigating RANK expression patterns helps identify new therapeutic approaches for bone disorders. Current research focuses on RANK's role in immune cell development and function. Santa Cruz Biotechnology monoclonal RANK antibodies support scientific discovery by providing reliable tools for exploring bone biology and immune system regulation.

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RANK Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

RANK Antibody (H-7)

sc-374360mouse IgG1 κ317-616 (h)WB, IP, IF, ELISAm, r, h
30
(10)

RANK Antibody (64C1385.1)

sc-59981mouse IgG1(h)WB, IP, FCMm, r, h
6
(2)

RANK Antibody (B-8)

sc-390655mouse IgG2a κ587-612 (m)WB, IP, IF, ELISAm, r
7
(4)

RANK Antibody (9A725)

sc-52951mouse IgG1 κ326-616 (h)WB, IF, IHC(P), FCMh
7
(1)

RANKL Antibody (G-1)

sc-377079mouse IgG1 κFL (h)WB, IP, IF, ELISAm, r, h
42
(15)

RANKL Antibody (12A668)

sc-52950mouse IgG11-317 (m)WB, IF, IHC(P)m, r, h
16
(5)

RANKL Antibody (12A380)

sc-59982mouse IgG11-317 (m)WB, IF, FCMm, r, h
5
(1)

RANK siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

RANK siRNA (h)

sc-42960hGene SilencingN/A0
(0)

RANK shRNA Plasmid (h)

sc-42960-SHhGene SilencingPuromycin0
(0)

RANK shRNA (h) Lentiviral Particles

sc-42960-VhGene SilencingPuromycin0
(0)

RANK siRNA (m)

sc-42961mGene SilencingN/A0
(0)

RANK shRNA Plasmid (m)

sc-42961-SHmGene SilencingPuromycin0
(0)

RANK shRNA (m) Lentiviral Particles

sc-42961-VmGene SilencingPuromycin0
(0)

RANKL siRNA (h)

sc-29464hGene SilencingN/A
3
(0)

RANKL shRNA Plasmid (h)

sc-29464-SHhGene SilencingPuromycin
3
(0)

RANKL shRNA (h) Lentiviral Particles

sc-29464-VhGene SilencingPuromycin
3
(0)

RANKL siRNA (m)

sc-37270mGene SilencingN/A
1
(0)

RANKL shRNA Plasmid (m)

sc-37270-SHmGene SilencingPuromycin
1
(0)

RANKL shRNA (m) Lentiviral Particles

sc-37270-VmGene SilencingPuromycin
1
(0)

RANK CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

RANK CRISPR/Cas9 KO Plasmid (h)

sc-400559Gene Knockouth0
(0)

RANK HDR Plasmid (h)

sc-400559-HDRHomology Directed Repairh0
(0)

RANK CRISPR/Cas9 KO Plasmid (m)

sc-423439Gene Knockoutm0
(0)

RANK HDR Plasmid (m)

sc-423439-HDRHomology Directed Repairm0
(0)

RANKL CRISPR/Cas9 KO Plasmid (h2)

sc-400304-KO-2Gene Knockouth0
(0)

RANKL HDR Plasmid (h2)

sc-400304-HDR-2Homology Directed Repairh0
(0)

RANKL CRISPR/Cas9 KO Plasmid (m)

sc-423448Gene Knockoutm0
(0)

RANK CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

RANK Double Nickase Plasmid (m)

sc-423439-NICGene Knockoutm0
(0)

RANKL Double Nickase Plasmid (h)

sc-400304-NICGene Knockouth0
(0)

RANKL Double Nickase Plasmid (h2)

sc-400304-NIC-2Gene Knockouth0
(0)

RANK CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

RANK CRISPR Activation Plasmid (h)

sc-400559-ACTGene Activationh0
(0)

RANK CRISPR Activation Plasmid (h2)

sc-400559-ACT-2Gene Activationh0
(0)

RANK Lentiviral Activation Particles (h)

sc-400559-LACGene Activationh0
(0)

RANK CRISPR Activation Plasmid (m)

sc-423439-ACTGene Activationm0
(0)

RANK CRISPR Activation Plasmid (m2)

sc-423439-ACT-2Gene Activationm0
(0)

RANK Lentiviral Activation Particles (m)

sc-423439-LACGene Activationm0
(0)

RANKL CRISPR Activation Plasmid (h)

sc-400304-ACTGene Activationh0
(0)

RANKL CRISPR Activation Plasmid (h2)

sc-400304-ACT-2Gene Activationh0
(0)