RANKL Antibody (12A668) is a mouse monoclonal IgG1, cited in 13 publications, provided at 50 µg/0.5 ml
raised against amino acids 1-317 of RANKL of mouse origin
recommended for detection of RANKL of mouse, rat and human origin by WB, IF and IHC(P)
See RANKL (G-1): sc-377079 for RANKL antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of RANKL (12A668): sc-52950.
m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for RANKL Antibody (12A668) for WB and IHC(P) applications. These reagents are now offered in bundles with RANKL Antibody (12A668) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Members of the tumor necrosis factor (TNF) receptor superfamily interact with signaling molecules of the TNF receptor-associated factor (TRAF) family to activate the NFκB and JNK pathways. RANK (receptor activator of NFκB) is a member of the TNFR family identified on dendritic cells. This type I membrane receptor is expressed in a broad range of tissues. The C-terminus of RANK is required for RANK to bind TRAF2, 5 and 6, and it is also necessary for stimulating NFκB activation. The ligand for this receptor, RANKL (also designated TRANCE, OPGL or ODF), is a type II transmembrane protein expressed primarily in lymphoid tissues and T cell lines. RANKL appears to be an important regulator of T cells and osteoclasts.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.