Date published: 2026-4-26

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Monoglyceride Lipase Activators

The chemical class termed Monoglyceride Lipase Activators encompasses a range of compounds that are hypothesized to influence the activity of Monoglyceride Lipase (MGL) indirectly. MGL plays a crucial role in lipid metabolism by hydrolyzing monoglycerides into free fatty acids and glycerol. The activity of MGL is intricately linked to the broader metabolic pathways in the cell, particularly those involving lipid processing and endocannabinoid signaling.

Compounds such as Forskolin and Caffeine, by modulating adenylate cyclase activity and altering cellular energy balance, can indirectly affect lipid metabolism pathways that intersect with MGL function. The presence of fatty acids like Palmitic Acid and Oleic Acid in this list highlights the significance of substrate availability in modulating MGL activity. These fatty acids can potentially enhance the availability of substrates for MGL, thus influencing its enzymatic action. Hormones like Insulin and Glucagon, known for their regulatory roles in lipid metabolism, further underscore the interconnectedness of metabolic regulation and MGL activity. Their influence on lipid processing pathways provides a mechanism through which MGL can be indirectly modulated.

SEE ALSO...

Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Activates adenylate cyclase, potentially influencing lipid metabolism pathways and indirectly MGL activity.

Palmitic Acid

57-10-3sc-203175
sc-203175A
25 g
100 g
$114.00
$286.00
2
(0)

A saturated fatty acid that may enhance MGL substrate availability, potentially affecting its activity.

Oleic Acid

112-80-1sc-200797C
sc-200797
sc-200797A
sc-200797B
1 g
10 g
100 g
250 g
$37.00
$104.00
$580.00
$1196.00
10
(1)

A monounsaturated fatty acid, might influence MGL activity by altering substrate availability.

Insulin

11061-68-0sc-29062
sc-29062A
sc-29062B
100 mg
1 g
10 g
$156.00
$1248.00
$12508.00
82
(1)

Regulates lipid metabolism, potentially affecting MGL activity through alterations in lipid processing.

Glucagon trifluoroacetic acid salt

9007-92-5 (free base)sc-495801
1 mg
$480.00
(0)

Influences lipid metabolism and could indirectly modulate MGL activity.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
50 g
100 g
250 g
1 kg
5 kg
$33.00
$67.00
$97.00
$192.00
$775.00
13
(1)

Alters lipid metabolism, potentially influencing MGL activity through changes in cellular energy balance.

Nicotinic Acid

59-67-6sc-205768
sc-205768A
250 g
500 g
$62.00
$124.00
1
(1)

A form of vitamin B3 that affects lipid metabolism, potentially influencing MGL activity.

Cholic acid

81-25-4sc-255020
sc-255020A
sc-255020B
sc-255020C
sc-255020D
25 g
100 g
500 g
1 kg
5 kg
$49.00
$123.00
$578.00
$1018.00
$4570.00
11
(1)

A bile acid that can affect lipid absorption and metabolism, potentially influencing MGL activity.

Pioglitazone

111025-46-8sc-202289
sc-202289A
1 mg
5 mg
$55.00
$125.00
13
(1)

A PPAR-gamma agonist, might indirectly influence MGL activity through modulation of lipid metabolism.

1,1-Dimethylbiguanide, Hydrochloride

1115-70-4sc-202000F
sc-202000A
sc-202000B
sc-202000C
sc-202000D
sc-202000E
sc-202000
10 mg
5 g
10 g
50 g
100 g
250 g
1 g
$20.00
$43.00
$63.00
$156.00
$260.00
$510.00
$31.00
37
(1)

Influences metabolic pathways, potentially affecting MGL activity through changes in lipid processing.