MF: C24H40O5 MW: 408.57 A non-denaturing ionic detergent.
General Laboratory Reagents
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Cholic acid (CAS 81-25-4)
3α,7α,12α-Trihydroxy-5β-cholanic acid; Cholanic acid
A non-denaturing ionic detergent
C 24H 40O 5 *
Certificate of Analysis for lot specific data (including water content).
Cholic acid, non-denaturing ionic detergent used for extraction of membrane proteins. Bile Acid
Soluble in alcohols, acetone, DMSO, methanol, and water (slightly).
200-201° C (lit.)
~583.9° C at 760 mmHg (Predicted)
20 D 1.56 (Predicted)
α20/D 35.5°±2.5°, c = 2 in ethanol
50 = 5.3 µM (mouse); TGR5: IC 50 = 6 µM (human); HCT-116: IC 50>50 µM (human); MCF7: IC 50 = 50 µM (human); GBM: IC 50>50 µM (human)
a: 4.98(20° C)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Rated 5 out of
Reich, et al. (PubMed ID 26420419) studied bile acid (BA) dependent cholangiocyte proliferation in TGR5 Knockout and wild type mice after being fed a cholic acid diet and under going common bile duct ligation (CBDL). -SCBT Publication Review
Date published: 2015-02-01
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