ZNF764, a protein belonging to the zinc finger protein family, serves as a transcription factor involved in the regulation of gene expression and various cellular processes. As a member of this protein family, ZNF764 contains multiple zinc finger motifs that enable it to bind to specific DNA sequences, thereby modulating the transcriptional activity of target genes. While the precise function of ZNF764 remains incompletely understood, it is proposed to play a role in diverse biological processes, including development, differentiation, and cell cycle regulation. Additionally, ZNF764 has been implicated in the regulation of apoptosis and DNA repair mechanisms, highlighting its involvement in maintaining cellular homeostasis and integrity.
Inhibiting ZNF764 activity poses a significant challenge due to its essential role in gene regulation and cellular processes. However, strategies for inhibiting ZNF764 could involve disrupting its DNA-binding activity or interfering with its interactions with other proteins or regulatory molecules. One approach to inhibition may involve targeting the zinc finger domains of ZNF764, which are essential for its binding to DNA sequences. By disrupting the integrity of these zinc finger motifs, either through small molecules or peptides, the ability of ZNF764 to bind to target gene promoters and regulate their transcriptional activity may be compromised. Additionally, inhibiting protein-protein interactions involved in ZNF764 function, such as interactions with co-regulatory proteins or chromatin-modifying enzymes, could also disrupt its transcriptional activity. Understanding the precise mechanisms underlying ZNF764 inhibition will provide valuable insights into its physiological roles and implications in development, disease, and cellular homeostasis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Diethylenetriaminepentaacetic acid | 67-43-6 | sc-214890 sc-214890A | 5 g 50 g | $74.00 $229.00 | 1 | |
Chelates metal ions, potentially influencing the metal-binding ability of zinc finger proteins like ZNF764. | ||||||
TPEN | 16858-02-9 | sc-200131 | 100 mg | $127.00 | 10 | |
A zinc chelator, potentially disrupting the zinc-binding properties of ZNF764's domains. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An HDAC inhibitor altering the chromatin state and possibly affecting ZNF764's transcriptional activity. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Affects DNA methylation, potentially influencing the DNA-binding of ZNF764. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
Affects transcription and can have indirect effects on ZNF764 function by altering transcriptional landscapes. | ||||||
RGFP966 | 1357389-11-7 | sc-507300 | 5 mg | $115.00 | ||
HDAC inhibitor potentially influencing transcriptional domains where ZNF764 might operate. | ||||||
I-BET 151 Hydrochloride | 1300031-49-5 (non HCl Salt) | sc-391115 | 10 mg | $450.00 | 2 | |
Affects transcriptional landscapes, possibly altering ZNF764's associated functions. | ||||||
UNC1999 | 1431612-23-5 | sc-475314 | 5 mg | $142.00 | 1 | |
Influences methylation states and possibly interacts with domains where ZNF764 operates. | ||||||
GSK126 | 1346574-57-9 | sc-490133 sc-490133A sc-490133B | 1 mg 5 mg 10 mg | $90.00 $238.00 $300.00 | ||
Affects chromatin marks which can potentially influence ZNF764's transcriptional activity. | ||||||
PFI-1 | 1403764-72-6 | sc-478504 | 5 mg | $96.00 | ||
Affects gene expression, potentially indirectly affecting ZNF764's functionality. | ||||||