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Diethylenetriaminepentaacetic acid (CAS 67-43-6)

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Alternate Names:
DTPA, Diethylenetriamine-N,N,N′,N′′,N′′-pentaacetic acid
Application:
Diethylenetriaminepentaacetic acid is an aminopolycarboxylic acid
CAS Number:
67-43-6
Purity:
≥98%
Molecular Weight:
393.35
Molecular Formula:
C14H23N3O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Diethylenetriaminepentaacetic acid is a chelating agent that forms stable complexes with metal ions, particularly with heavy metals such as lead and cadmium. It functions by binding to metal ions through multiple coordination sites, preventing their participation in chemical reactions. Diethylenetriaminepentaacetic Acid′s mechanism of action involves the formation of a stable complex with metal ions, effectively sequestering them and preventing their interaction with other molecules. This chelating property may be useful in experimental applications for removing metal ions from solutions or biological systems, allowing for the study of metal ion effects on biological processes. Diethylenetriaminepentaacetic acid can also be used to remove metal ions from industrial waste streams, contributing to environmental remediation efforts. Its ability to form stable complexes with metal ions may be useful in experimental for studying metal ion interactions and their impact on biological systems.


Diethylenetriaminepentaacetic acid (CAS 67-43-6) References

  1. Time-resolved fluoroimmunoassay.  |  Degan, P., et al. 1999. Mol Biotechnol. 13: 215-22. PMID: 10934534
  2. Diethylenetriaminepentaacetic acid enhances thyroid hormone action by a transcriptional mechanism.  |  Sciaudone, MP., et al. 2004. Biol Trace Elem Res. 99: 219-31. PMID: 15235154
  3. Diethylenetriaminepentaacetic acid-gadolinium (DTPA-Gd)-conjugated polysuccinimide derivatives as magnetic resonance imaging contrast agents.  |  Lee, HY., et al. 2006. Bioconjug Chem. 17: 700-6. PMID: 16704207
  4. Effect of carboxyl-group of D-glutamic acid or gamma-carboxy-D-glutamic acid as N-terminal amino acid of (111)in-diethylenetriaminepentaacetic acid-octreotide on accumulation of radioactivity in kidney.  |  Akizawa, H., et al. 2007. Biol Pharm Bull. 30: 2226-8. PMID: 17978507
  5. Comparison of the Relative Renal Function Calculated with 99mTc-Diethylenetriaminepentaacetic Acid and 99mTc-Dimercaptosuccinic Acid in Children.  |  Çelik, T., et al. 2014. World J Nucl Med. 13: 149-53. PMID: 25538484
  6. Performance of magnetic graphene oxide/diethylenetriaminepentaacetic acid nanocomposite for the tetracycline and ciprofloxacin adsorption in single and binary systems.  |  Li, MF., et al. 2018. J Colloid Interface Sci. 521: 150-159. PMID: 29567603
  7. An electronic technetium-99m-diethylenetriaminepentaacetic acid glomerular filtration rate spreadsheet with novel embedded quality assurance features.  |  Klein, R., et al. 2019. Nucl Med Commun. 40: 30-40. PMID: 30362986
  8. Adsorption of Hg (II) ions from aqueous solution by diethylenetriaminepentaacetic acid-modified cellulose.  |  Li, B., et al. 2019. Int J Biol Macromol. 122: 149-156. PMID: 30393133
  9. Chromium removal from aqueous solutions using new silica gel conjugates of desferrioxamine or diethylenetriaminepentaacetic acid.  |  Rasheed, A., et al. 2020. Environ Sci Pollut Res Int. 27: 15635-15644. PMID: 32078726
  10. Corrigendum to 'Efficient adsorption of Mn(II) by layered double hydroxides intercalated with diethylenetriaminepentaacetic acid and the mechanistic study' [J. Environ. Sci. 85 (2019) 56-65].  |  Huang, M., et al. 2020. J Environ Sci (China). 90: 411-412. PMID: 32081339
  11. Europium-Diethylenetriaminepentaacetic Acid Loaded Radioluminescence Liposome Nanoplatform for Effective Radioisotope-Mediated Photodynamic Therapy.  |  Lee, W., et al. 2020. ACS Nano. 14: 13004-13015. PMID: 32820903
  12. Isotherm, kinetics, and adsorption mechanism studies of diethylenetriaminepentaacetic acid-modified banana/pomegranate peels as efficient adsorbents for removing Cd(II) and Ni(II) from aqueous solution.  |  Wang, F., et al. 2022. Environ Sci Pollut Res Int. 29: 3051-3061. PMID: 34383214

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Diethylenetriaminepentaacetic acid, 5 g

sc-214890
5 g
$74.00

Diethylenetriaminepentaacetic acid, 50 g

sc-214890A
50 g
$229.00

What is UN Number for DTPA

Asked by: Luke912
This chemical is not regulated for transport so there is not a UNID number.
Answered by: Technical Support
Date published: 2019-10-24
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Rated 5 out of 5 by from AwesomeUsed this chemical within my buffer when using DHE probe for superoxide quantification. Everything went well!
Date published: 2018-08-15
Rated 5 out of 5 by from Various publications cite the use of DiethylenetriaminepentaaceticVarious publications cite the use of Diethylenetriaminepentaacetic acid as a metal ion chelator similar to EDTA. -SCBT Publication Review
Date published: 2015-07-20
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Diethylenetriaminepentaacetic acid is rated 5.0 out of 5 by 2.
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