ZNF746 Inhibitors refers to a class of chemical compounds that specifically target and impede the function of the Zinc Finger Protein 746 (ZNF746). ZNF746 is a transcription factor that plays a crucial role in various cellular processes, particularly in the regulation of gene expression. Transcription factors like ZNF746 exert their influence by binding to specific DNA sequences, thereby modulating the transcription of target genes. In this context, ZNF746 Inhibitors are designed to interfere with the normal activity of ZNF746, leading to a downstream impact on the transcriptional landscape within cells.
ZNF746 Inhibitors are characterized by their ability to interact selectively with ZNF746, disrupting its binding affinity to DNA or altering its conformational structure. This inhibition may occur through various mechanisms, such as competitive binding at the DNA-binding site of ZNF746 or by inducing structural changes that render ZNF746 less effective in its regulatory function. Researchers often employ a range of chemical modifications and optimization strategies to enhance the potency and specificity of these inhibitors. The development of ZNF746 Inhibitors is of significant interest in the field of molecular biology, offering a tool to investigate the precise roles of ZNF746 in cellular processes and potentially revealing insights into the broader regulatory networks governing gene expression. The exploration of ZNF746 Inhibitors contributes to the ongoing effort to decipher the intricate molecular mechanisms underlying cellular functions and may open avenues for further research in the realm of gene regulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a nucleoside analogue of cytidine that can be incorporated into DNA during replication. It inhibits DNA methyltransferases, leading to hypomethylation of DNA and potentially affecting ZNF746's ability to bind to its target DNA sequences. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor that alters chromatin structure and can affect transcription factor binding, potentially influencing ZNF746 activity. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Etoposide is a topoisomerase II inhibitor that interferes with DNA replication and transcription, potentially affecting ZNF746-mediated transcriptional regulation. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Actinomycin D binds to DNA and blocks the transcription process, which can disrupt ZNF746's function as a transcriptional regulator. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
Mithramycin A binds to DNA and inhibits RNA polymerase, potentially affecting the transcriptional activity of ZNF746. | ||||||
Ellipticine | 519-23-3 | sc-200878 sc-200878A | 10 mg 50 mg | $145.00 $569.00 | 4 | |
Ellipticine intercalates with DNA and inhibits topoisomerase II, potentially interfering with ZNF746's function. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein is a tyrosine kinase inhibitor that can inhibit signal transduction pathways, potentially affecting ZNF746 activity downstream of these pathways. | ||||||
Mitoxantrone | 65271-80-9 | sc-207888 | 100 mg | $285.00 | 8 | |
Mitoxantrone intercalates with DNA and inhibits topoisomerase II, which could affect DNA replication and transcription, influencing ZNF746's function. | ||||||
Alsterpaullone | 237430-03-4 | sc-202453 sc-202453A | 1 mg 5 mg | $68.00 $312.00 | 2 | |
Alsterpaullone is a cyclin-dependent kinase inhibitor that can affect cell cycle progression and DNA replication, potentially influencing ZNF746's function. | ||||||
Aphidicolin | 38966-21-1 | sc-201535 sc-201535A sc-201535B | 1 mg 5 mg 25 mg | $84.00 $306.00 $1104.00 | 30 | |
Aphidicolin is an inhibitor of DNA polymerase, which can affect DNA replication and potentially influence ZNF746's function. | ||||||