ZNF512 inhibitors refer to a class of compounds that specifically target and modulate the activity of the zinc finger protein 512 (ZNF512), a transcription factor that plays a critical role in regulating gene expression. Zinc finger proteins, in general, are characterized by their zinc-coordinating domains, which allow them to bind to DNA and interact with other proteins, influencing cellular processes such as transcriptional regulation, cell differentiation, and growth. ZNF512 belongs to a broader family of zinc finger proteins and is involved in the fine-tuning of various cellular pathways through its regulation of gene expression. Inhibitors of ZNF512 typically work by interfering with its ability to bind to DNA or by altering its interaction with co-regulatory proteins, thus affecting the downstream gene targets and cellular responses regulated by ZNF512.
In the context of biochemical research, ZNF512 inhibitors are valuable tools for studying the precise molecular mechanisms controlled by this transcription factor. By modulating the activity of ZNF512, researchers can observe changes in gene expression patterns, providing insights into how this protein contributes to cellular functions such as signal transduction, cellular proliferation, and differentiation. These inhibitors are typically small molecules that can penetrate cellular membranes and disrupt the normal functioning of ZNF512, leading to altered transcriptional activity. The detailed study of these interactions allows for a better understanding of the complex networks involved in cellular homeostasis and the regulatory roles of transcription factors like ZNF512 in various biological processes. Researchers are particularly interested in the structural characteristics of these inhibitors and their binding affinities, which help elucidate the exact mechanism of action at the molecular level.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
These inhibitors can alter chromatin structure and gene expression, potentially impacting ZNF512-related transcriptional regulation. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
By affecting DNA methylation, these inhibitors might influence gene expression patterns relevant to ZNF512. | ||||||
Ruxolitinib | 941678-49-5 | sc-364729 sc-364729A sc-364729A-CW | 5 mg 25 mg 25 mg | $246.00 $490.00 $536.00 | 16 | |
These inhibitors can modulate the JAK/STAT pathway, potentially impacting signal transduction processes involving ZNF512. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Targeting the PI3K/Akt pathway, which is involved in cell survival and proliferation, might influence ZNF512 activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
By modulating the MAPK pathway, these inhibitors could indirectly influence ZNF512's role in signaling cascades. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
By inhibiting mTOR, these compounds can affect cell growth and protein synthesis, potentially impacting ZNF512 activity. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
Targeting bromodomain and extra-terminal motif proteins, these inhibitors can influence gene expression regulation linked to ZNF512. | ||||||
17-AAG | 75747-14-7 | sc-200641 sc-200641A | 1 mg 5 mg | $66.00 $153.00 | 16 | |
These inhibitors can affect protein stability and function, potentially impacting ZNF512. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
By inhibiting NF-κB, a key transcription factor, these compounds might indirectly impact ZNF512's transcriptional network. | ||||||
XAV939 | 284028-89-3 | sc-296704 sc-296704A sc-296704B | 1 mg 5 mg 50 mg | $35.00 $115.00 $515.00 | 26 | |
These inhibitors can modulate Wnt signaling, potentially influencing ZNF512's role in gene regulation. |