ZNF512 Antibody (A-1): sc-398142
- ZNF512 Antibody (A-1) is a mouse monoclonal IgG2b κ ZNF512 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 41-62 near the N-terminus of ZNF512 of human origin
- ZNF512 Antibody (A-1) is recommended for detection of ZNF512 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- Anti-ZNF512 Antibody (A-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ZNF512 Antibody (A-1) for WB applications. These reagents are now offered in bundles with ZNF512 Antibody (A-1) (see ordering information below).
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ZNF512 Antibody (A-1) is a mouse monoclonal IgG2b kappa light chain antibody that detects ZNF512 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-ZNF512 antibody (A-1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ZNF512, also known as zinc finger protein 512, is a 567 amino acid protein characterized by four C2H2-type zinc fingers, which are crucial for DNA binding and transcriptional regulation. Located primarily in the nucleus, ZNF512 (A-1) antibody targets a protein that plays a significant role in modulating gene expression, vital for numerous cellular processes, including development and differentiation. The gene encoding ZNF512 is situated on chromosome 2, a region associated with various genetic disorders, highlighting the importance of ZNF512 in maintaining genomic integrity and proper cellular function. Understanding the interactions and regulatory mechanisms of ZNF512 can provide insights into potential implications in diseases linked to chromosomal abnormalities, making ZNF512 (A-1) monoclonal antibody an essential tool for researchers studying gene regulation and associated pathways.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ZNF512 Antibody (A-1) References:
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. | Hillier, LW., et al. 2005. Nature. 434: 724-31. PMID: 15815621
- Evidence for an ancestral alphoid domain on the long arm of human chromosome 2. | Avarello, R., et al. 1992. Hum Genet. 89: 247-9. PMID: 1587535
- ABCA12 is the major harlequin ichthyosis gene. | Thomas, AC., et al. 2006. J Invest Dermatol. 126: 2408-13. PMID: 16902423
- Spectrum of ALMS1 variants and evaluation of genotype-phenotype correlations in Alström syndrome. | Marshall, JD., et al. 2007. Hum Mutat. 28: 1114-23. PMID: 17594715
- Compound heterozygous ABCA12 mutations including a novel nonsense mutation underlie harlequin ichthyosis. | Akiyama, M., et al. 2007. Dermatology. 215: 155-9. PMID: 17684380
- Alström syndrome. | Marshall, JD., et al. 2007. Eur J Hum Genet. 15: 1193-202. PMID: 17940554
- Origin of human chromosome 2: an ancestral telomere-telomere fusion. | IJdo, JW., et al. 1991. Proc Natl Acad Sci U S A. 88: 9051-5. PMID: 1924367
- Finger proteins and DNA-specific recognition: distinct patterns of conserved amino acids suggest different evolutionary modes. | Payre, F. and Vincent, A. 1988. FEBS Lett. 234: 245-50. PMID: 3292287
- Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs. | Rosenfeld, R. and Margalit, H. 1993. J Biomol Struct Dyn. 11: 557-70. PMID: 8129873
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZNF512 Antibody (A-1) | sc-398142 | 200 µg/ml | $316.00 | |||
ZNF512 Antibody (A-1): m-IgG Fc BP-HRP Bundle | sc-530703 | 200 µg Ab; 10 µg BP | $354.00 | |||
ZNF512 Antibody (A-1): m-IgGκ BP-HRP Bundle | sc-524230 | 200 µg Ab, 40 µg BP | $354.00 | |||
ZNF512 Antibody (A-1): m-IgG2b BP-HRP Bundle | sc-550214 | 200 µg Ab; 10 µg BP | $354.00 | |||
ZNF512 Antibody (A-1) AC | sc-398142 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ZNF512 Antibody (A-1) HRP | sc-398142 HRP | 200 µg/ml | $316.00 | |||
ZNF512 Antibody (A-1) FITC | sc-398142 FITC | 200 µg/ml | $330.00 | |||
ZNF512 Antibody (A-1) PE | sc-398142 PE | 200 µg/ml | $343.00 | |||
ZNF512 Antibody (A-1) Alexa Fluor® 488 | sc-398142 AF488 | 200 µg/ml | $357.00 | |||
ZNF512 Antibody (A-1) Alexa Fluor® 546 | sc-398142 AF546 | 200 µg/ml | $357.00 | |||
ZNF512 Antibody (A-1) Alexa Fluor® 594 | sc-398142 AF594 | 200 µg/ml | $357.00 | |||
ZNF512 Antibody (A-1) Alexa Fluor® 647 | sc-398142 AF647 | 200 µg/ml | $357.00 | |||
ZNF512 Antibody (A-1) Alexa Fluor® 680 | sc-398142 AF680 | 200 µg/ml | $357.00 | |||
ZNF512 Antibody (A-1) Alexa Fluor® 790 | sc-398142 AF790 | 200 µg/ml | $357.00 | |||
ZNF512 (A-1) Neutralizing Peptide | sc-398142 P | 100 µg/0.5 ml | $68.00 |