ZNF410 Activators
The functional activity of ZNF410, a zinc finger protein, can be influenced by a variety of chemical compounds that affect specific cellular signaling pathways. Some of these compounds work by elevating intracellular cyclic AMP (cAMP) levels, thereby enhancing the activity of protein kinase A (PKA), which in turn can phosphorylate transcription factors involved in the regulation of ZNF410 expression. Similarly, analogs of diacylglycerol such as phorbol esters activate protein kinase C (PKC), a key player in the modulation of gene expression, potentially leading to the upregulation of ZNF410. Modulating intracellular calcium levels also plays a role in the activation of ZNF410, as calcium-dependent signaling pathways are integral to the regulation of many zinc finger proteins. Ionophores that increase cellular calcium can indirectly activate these pathways, influencing the activity of ZNF410.
Other compounds exert their influence on ZNF410 by altering chromatin structure and the epigenetic landscape. Inhibitors of histone deacetylases and DNA methyltransferases can induce a more relaxed chromatin state and reduce methylation levels at gene loci, respectively, potentially enhancing the transcriptional activity of ZNF410 by improving its access to DNA binding sites. Furthermore, agents that influence the cellular redox state may also impact ZNF410 function, as oxidative stress can affect the binding of transcription factors to DNA.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
This compound activates adenylate cyclase, increasing cAMP levels in cells. The rise in cAMP may enhance the activity of cAMP-dependent protein kinase A (PKA), which can phosphorylate transcription factors that regulate ZNF410 expression. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
As a diacylglycerol analog, PMA activates protein kinase C (PKC), which can lead to the phosphorylation of factors that control gene expression, potentially increasing the transcription of ZNF410. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
This ionophore increases intracellular calcium levels, which could activate calcium-dependent signaling pathways, potentially enhancing the transcriptional activity of ZNF410. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
As an inhibitor of histone deacetylases, Trichostatin A may lead to a more relaxed chromatin structure around the ZNF410 gene, potentially facilitating its transcription. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
This DNA methyltransferase inhibitor could decrease methylation levels at the ZNF410 gene locus, potentially upregulating its expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
As a histone deacetylase inhibitor, Sodium butyrate can alter chromatin structure and increase gene expression, potentially including that of ZNF410. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
A metabolite of vitamin A, retinoic acid can modulate gene expression through its nuclear receptors, which might include the regulation of ZNF410 expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
The main catechin in green tea, EGCG, may modulate various signaling pathways, possibly influencing the expression of genes such as ZNF410. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
This compound inhibits glycogen synthase kinase-3 (GSK-3), which may lead to the stabilization and activation of transcription factors that upregulate ZNF410 expression. | ||||||
Ademetionine | 29908-03-0 | sc-278677 sc-278677A | 100 mg 1 g | $180.00 $655.00 | 2 | |
As a methyl donor, this compound could influence DNA methylation patterns, potentially affecting the methylation status of the ZNF410 gene and its expression levels. | ||||||