ZNF354A inhibitors belong to a specific chemical class designed to modulate the activity of the zinc finger protein 354A (ZNF354A). Zinc finger proteins are a diverse group of nucleic acid-binding proteins that play crucial roles in various cellular processes, including transcriptional regulation and DNA repair. ZNF354A, in particular, is involved in gene expression control and has been implicated in the regulation of cellular proliferation and differentiation. The development of ZNF354A inhibitors stems from the recognition of the protein's significance in these cellular processes.
ZNF354A inhibitors are designed to interact selectively with the target protein, disrupting its normal function or hindering its interaction with other cellular components. This class of compounds typically exhibits a high degree of specificity, aiming to influence ZNF354A without interfering with the activity of other proteins. The design and synthesis of ZNF354A inhibitors often involve a deep understanding of the protein's structure and binding sites, allowing researchers to tailor molecules that can bind to specific regions of ZNF354A and alter its activity. These inhibitors may function through various mechanisms, such as competitive binding at the active site or inducing conformational changes that hinder the protein's normal function. The development of ZNF354A inhibitors represents a significant advancement in the field of molecular pharmacology, offering a potential means to explore and understand the intricate regulatory networks within cells by selectively modulating the activity of this specific zinc finger protein.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Downregulates transcription factors and can disrupt the transcription of genes regulated by ZNF354A. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Affects gene expression by modulating transcription factors, potentially altering ZNF354A activity. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
Disrupts BET domain binding to chromatin, possibly affecting genes controlled by ZNF354A. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
Proteasome inhibitor that can increase the levels of transcription factors and influence ZNF354A's role. | ||||||
I-BET 151 Hydrochloride | 1300031-49-5 (non HCl Salt) | sc-391115 | 10 mg | $450.00 | 2 | |
BET bromodomain inhibitor, potentially altering the expression of ZNF354A target genes. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA methyltransferase inhibitor that can change the expression of genes potentially regulated by ZNF354A. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Histone deacetylase inhibitor that can modify chromatin structure affecting ZNF354A target gene expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Modulates transcription factor activity, which could alter ZNF354A-mediated gene transcription. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $52.00 $87.00 | 7 | |
Alters protease activity and could impact the stability of transcription factors like ZNF354A. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Histone deacetylase inhibitor that can potentially modify the transcriptional activity of ZNF354A. | ||||||