ZNF34 Inhibitors
Zinc finger protein 34 (ZNF34) is a member of the zinc finger protein family, a diverse group of proteins that play vital roles in DNA recognition, RNA packaging, transcriptional activation, regulation of apoptosis, and protein folding and assembly. Zinc finger domains are small, functional units within these proteins that are capable of coordinating zinc ions to stabilize their folds, with the most common type being the C2H2-type zinc finger.The defining feature of ZNF34, as with other zinc finger proteins, is the presence of these zinc finger motifs. Each motif typically consists of a short beta-sheet and an alpha-helix, held together by a zinc ion coordinated by conserved cysteine and histidine residues. These structures enable ZNF34 to bind to DNA, and potentially RNA, in a sequence-specific manner.
As a transcription factor, ZNF34 is likely involved in the transcriptional regulation of genes, acting either as an activator that promotes gene expression or a repressor that diminishes it. The exact genes and cellular pathways that ZNF34 regulates are not fully characterized, but given the broad influence of zinc finger proteins on gene expression, it may impact a range of cellular processes including development, cell differentiation, and the cell cycle.Mutations or dysregulation in ZNF34 can have profound implications on cellular function and organismal development. Aberrant ZNF34 activity or expression levels can lead to malfunctions in gene regulation, which may contribute to diseases such as cancers, developmental disorders, and other conditions where transcriptional misregulation plays a key role.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, potentially affecting gene expression patterns and indirectly influencing ZNF34 activity. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
A histone deacetylase (HDAC) inhibitor, which may alter chromatin structure and gene expression, potentially impacting ZNF34. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Another HDAC inhibitor, potentially affecting gene regulation and indirectly influencing ZNF34 activity. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $131.00 $515.00 | 2 | |
A DNA methyltransferase inhibitor, which can alter gene expression and potentially impact ZNF34. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
Similar to 5-Azacytidine, affects DNA methylation and gene expression, potentially influencing ZNF34. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $90.00 $212.00 | 24 | |
A selective HDAC inhibitor, which may have implications for gene regulation involving ZNF34. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
A BET bromodomain inhibitor, potentially influencing gene expression and regulatory mechanisms involving ZNF34. | ||||||
I-BET 151 Hydrochloride | 1300031-49-5 (non HCl Salt) | sc-391115 | 10 mg | $450.00 | 2 | |
Another BET bromodomain inhibitor, which can affect transcription regulation, potentially impacting ZNF34. | ||||||
A-366 | 1527503-11-2 | sc-507495 | 10 mg | $195.00 | ||
A G9a/GLP histone methyltransferase inhibitor, potentially altering epigenetic marks and gene expression relevant to ZNF34. | ||||||
UNC1999 | 1431612-23-5 | sc-475314 | 5 mg | $142.00 | 1 | |
A selective EZH2/EZH1 inhibitor, potentially affecting gene expression patterns relevant to ZNF34. | ||||||