ZNF165 inhibitors are a category of chemical compounds designed to target and modulate the activity of ZNF165, which stands for Zinc Finger Protein 165. ZNF165 is a member of the zinc finger protein family, a group of transcription factors known for their ability to bind to specific DNA sequences and regulate gene expression. These proteins play pivotal roles in various cellular processes, including development, differentiation, and response to environmental signals. ZNF165, in particular, contains multiple zinc finger motifs that enable it to interact with DNA in a sequence-specific manner. Inhibitors of ZNF165 are developed to interact with this specific transcription factor, potentially influencing its DNA binding properties, its interactions with other cellular proteins, or its roles in regulating gene expression.
Structurally, ZNF165 inhibitors are meticulously designed to engage specific regions or binding sites on the ZNF165 protein, primarily targeting its zinc finger domains. This interaction may disrupt the normal functioning of ZNF165, potentially affecting its ability to bind to DNA and modulate the transcription of target genes. The mechanisms by which ZNF165 inhibitors exert their effects can vary, but their primary objective is to serve as valuable tools for researchers studying the roles of ZNF165 in various cellular contexts. Investigating the biochemical and functional aspects of ZNF165 and its modulation by inhibitors can contribute to a deeper understanding of gene regulation, cellular differentiation, and the broader field of molecular and cellular biology. Ultimately, such research can offer insights into the intricate molecular mechanisms that govern fundamental cellular processes and their potential regulation by ZNF165 inhibition.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a DNA methyltransferase inhibitor. It can demethylate DNA and reactivate silenced genes. By modulating the epigenetic landscape, it can influence the expression of ZNF165. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A is a histone deacetylase (HDAC) inhibitor. HDACs influence gene expression by altering chromatin structure. Inhibiting them can lead to changes in the expression profile of many genes, potentially including ZNF165. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
JQ1 is a BET bromodomain inhibitor. By inhibiting bromodomains, it affects the reading of acetylated histones, potentially altering the transcription of certain genes, possibly including ZNF165. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $131.00 $515.00 | 2 | |
RG108 is another DNA methyltransferase inhibitor. Similar to 5-Azacytidine, it can demethylate DNA and influence gene expression patterns, potentially impacting ZNF165 expression. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Vorinostat is an HDAC inhibitor. By altering histone acetylation patterns, it can influence the transcriptional landscape of the cell, which may impact ZNF165 expression. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
Decitabine, like 5-Azacytidine, inhibits DNA methyltransferases. It can alter gene expression by changing DNA methylation patterns, which could influence ZNF165. | ||||||
Mocetinostat | 726169-73-9 | sc-364539 sc-364539B sc-364539A | 5 mg 10 mg 50 mg | $214.00 $247.00 $1463.00 | 2 | |
Mocetinostat is an HDAC inhibitor that, by altering histone acetylation, can change gene expression profiles in cells, possibly affecting ZNF165. | ||||||
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $218.00 $634.00 | 1 | |
Romidepsin is another HDAC inhibitor. Its influence on histone acetylation can lead to changes in gene transcription, which may include effects on ZNF165. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $90.00 $212.00 | 24 | |
Entinostat is an HDAC inhibitor. By influencing the acetylation of histones, it can modulate the transcription of various genes, potentially impacting ZNF165 expression. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $200.00 | 9 | |
Panobinostat, another HDAC inhibitor, can influence gene expression through its effects on histone acetylation, which may impact ZNF165. | ||||||