ZNF12 Activators
ZNF12 activators encompass a range of compounds that influence various signaling pathways and epigenetic mechanisms, which can lead to an indirect increase in the activity or expression of ZNF12. Trichostatin A and Sodium butyrate can change the chromatin architecture around the ZNF12 gene, facilitating easier access for transcription machinery and subsequent upregulation of ZNF12 expression. 5-Aza-2'-deoxycytidine may demethylate DNA at the promoter region of ZNF12, enhancing its transcription.
In addition, compounds that affect intracellular signaling pathways and transcription factor activities, such as Vitamin D3, Forskolin, and Retinoic acid, can also modulate the expression levels of ZNF12. Forskolin, by increasing cAMP, may activate protein kinase A, leading to changes in transcription factor dynamics that can elevate ZNF12 transcription. Similarly, signaling modulators like LY294002, PD98059, and SP600125 can impact the activity of downstream transcription factors on key signaling pathways like PI3K/Akt, MAPK/ERK, and JNK, respectively, resulting in enhanced ZNF12 expression. Moreover, Rapamycin can influence overall protein synthesis and gene expression, which might include effects on ZNF12 expression levels.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
A DNA methyltransferase inhibitor, it can lead to hypomethylation of gene promoters, possibly increasing ZNF12 expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A histone deacetylase inhibitor, it may result in a more relaxed chromatin state, enhancing the transcription of certain genes including ZNF12. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Also a histone deacetylase inhibitor, it may promote the expression of ZNF12 by altering chromatin structure. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Involved in the regulation of gene expression, it can modulate transcription factor activity and potentially upregulate ZNF12. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels, which may lead to the activation of transcription factors affecting ZNF12 expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
By modulating gene expression, it can influence the transcription of various genes, including potentially ZNF12. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Affects various signaling pathways and might influence transcription factor activity and gene expression profiles, including ZNF12. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates protein kinase C, which can lead to altered transcription factor activities and possibly the expression of ZNF12. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor, which can affect signaling pathways and potentially influence the transcriptional activity of ZNF12. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
An ERK pathway inhibitor, it can modulate transcription factor activity indirectly affecting ZNF12 expression. | ||||||