Wnt-7a Activators
Wnt-7a activators belong to a class of chemical compounds designed to selectively target and modulate the activity of Wnt-7a, a secreted signaling protein that is a member of the Wnt family. Wnt-7a, like other Wnt proteins, plays a pivotal role in various developmental and cellular processes, particularly during embryogenesis, tissue regeneration, and homeostasis in adult organisms. It acts as a ligand for cell surface receptors, initiating a cascade of intracellular events that regulate gene expression and influence cell fate decisions. Wnt-7a is involved in several signaling pathways, including the canonical Wnt/β-catenin pathway and non-canonical pathways, which are critical for processes such as cell proliferation, differentiation, and tissue patterning.
Activation of Wnt-7a by specific chemical compounds trigger downstream signaling events and cellular responses associated with the activation of Wnt pathways. These activators are designed to enhance the binding of Wnt-7a to its receptors, thereby facilitating the initiation of intracellular signaling cascades. The modulation of Wnt-7a activity can have profound effects on embryonic development, tissue regeneration, and tissue homeostasis in adults. Understanding the mechanisms and effects of Wnt-7a activators is of significant interest in the field of developmental biology and cell signaling research, as it can shed light on the intricate regulatory networks that govern cellular behavior and tissue morphogenesis. These compounds serve as valuable tools for investigating the roles of Wnt-7a in various cellular contexts and uncovering its contributions to normal developmental processes and tissue maintenance.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid may induce Wnt-7a expression by modulating gene transcription in developmental pathways. It is known to interact with pathways that overlap with Wnt signaling. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride could upregulate Wnt-7a through inhibition of GSK-3β, a negative regulator of the Wnt/β-catenin signaling pathway, thus potentially enhancing Wnt signaling. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Cholecalciferol might influence Wnt-7a expression by its role in cellular growth and differentiation, processes in which Wnt signaling is often involved. | ||||||
Bisphenol A | 80-05-7 | sc-391751 sc-391751A | 100 mg 10 g | $300.00 $490.00 | 5 | |
Bisphenol A could potentially induce Wnt-7a expression as it interferes with hormonal signaling pathways, which might intersect with Wnt signaling pathways. | ||||||
Folic Acid | 59-30-3 | sc-204758 | 10 g | $72.00 | 2 | |
Folic acid may modulate Wnt-7a expression due to its role in DNA synthesis and repair, processes that can influence gene expression patterns including those in the Wnt signaling pathway. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
SB431542, while primarily a TGF-β inhibitor, might indirectly affect Wnt-7a expression due to the crosstalk between TGF-β and Wnt signaling pathways in regulating cell fate and differentiation. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Valproic acid, a histone deacetylase inhibitor, could influence Wnt-7a expression by altering chromatin structure and thus affecting gene expression, including Wnt pathway genes. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A may upregulate Wnt-7a expression by inhibiting histone deacetylase, leading to changes in chromatin structure and gene expression, which could impact Wnt signaling genes. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
Nicotinamide could potentially enhance Wnt-7a expression through its role in cellular energy metabolism, which is crucial for cell signaling and gene expression. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
DL-Sulforaphane may affect Wnt-7a expression through its role in cellular detoxification and oxidative stress response, processes that are known to interact with Wnt signaling pathways. | ||||||