WDR13 inhibitors belong to a specific class of chemical compounds designed to target and modulate the activity of the WDR13 protein. The term "WDR13" stands for WD Repeat Domain 13, which is a protein characterized by the presence of multiple WD40 repeat domains. These WD40 repeat domains serve as protein-protein interaction modules, allowing WDR13 to participate in various cellular processes. WDR13 itself is known to play a role in various biological functions, including gene expression regulation, cell cycle progression, and protein degradation through the ubiquitin-proteasome pathway. Inhibitors of WDR13 are synthesized with the aim of disrupting or attenuating the protein's function, leading to alterations in cellular processes where WDR13 is involved.
WDR13 inhibitors can take on diverse forms, including small organic molecules or peptides, designed to bind to specific sites on the WDR13 protein, thereby interfering with its normal function. The structural diversity of these inhibitors allows for a range of approaches in designing molecules that can effectively disrupt WDR13 activity. Through extensive research and experimentation, scientists aim to elucidate the mechanisms by which WDR13 inhibitors interact with the protein and understand their impact on cellular pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Inhibits mTOR pathway, which could intersect with WDR13-related signaling and protein synthesis control. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Inhibits PI3K, upstream of mTOR signaling, potentially affecting WDR13 function indirectly. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Another PI3K inhibitor, could alter WDR13 function through modulation of PI3K-dependent pathways. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
HDAC inhibitor, could affect WDR13 by altering chromatin structure and gene expression. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA methyltransferase inhibitor, potentially impacting WDR13 expression by epigenetic modulation. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
MEK inhibitor, could interfere with the MAPK/ERK pathway, which may intersect with WDR13 signaling. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor, potentially affecting pathways that WDR13 may be involved in. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
p38 MAPK inhibitor, could disrupt cellular processes involving WDR13. | ||||||
Apocynin | 498-02-2 | sc-203321 sc-203321A sc-203321B sc-203321C | 1 g 10 g 100 g 500 g | $27.00 $68.00 $116.00 $360.00 | 74 | |
Inhibits NADPH-oxidase, which could influence oxidative stress pathways linked to WDR13. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
ROCK inhibitor, could affect cytoskeletal dynamics, potentially influencing WDR13's cellular context. | ||||||