WBSCR11 Activators
WBSCR11 Activators refers to a group of compounds or molecules that have been identified for their ability to modulate the activity of the WBSCR11 gene. WBSCR11, also known as Williams-Beuren syndrome chromosomal region 11, is a gene located on chromosome 7 and plays a crucial role in various cellular processes. Activators of WBSCR11 are substances that can enhance the expression or function of this gene, leading to specific biological effects.
These activators are of particular interest to researchers studying the molecular mechanisms underlying genetic disorders and the normal functioning of genes within the human genome. By influencing WBSCR11, these compounds may contribute to our understanding of the gene's role in developmental processes, gene regulation, or other biological pathways. Scientists employ various techniques and assays to identify and characterize WBSCR11 activators, often utilizing cell cultures or model organisms for experimentation. The elucidation of the mechanisms through which these activators interact with WBSCR11 can provide valuable insights into gene regulation and expression, shedding light on fundamental biological processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is a diterpene that directly stimulates adenylate cyclase, thereby increasing cAMP levels in cells. Elevated cAMP activates PKA, which can phosphorylate and thereby enhance the activity of WBSCR17 by promoting cellular processes in which WBSCR17 is involved. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
Isobutylmethylxanthine (IBMX) is a non-selective inhibitor of phosphodiesterases, which prevents the breakdown of cAMP and cGMP, leading to their accumulation. The increase in cAMP levels can further activate PKA, potentially enhancing WBSCR17 activity associated with PKA signaling pathways. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram is a selective phosphodiesterase-4 inhibitor, which elevates intracellular cAMP by preventing its degradation. Higher cAMP levels lead to activation of PKA, which may enhance the functions of WBSCR17 through cAMP-dependent signaling pathways. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Phorbol 12-myristate 13-acetate (PMA) is a potent activator of protein kinase C (PKC). PKC activation can lead to phosphorylation events that indirectly enhance WBSCR17 activity through signaling cascades that involve PKC. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a polyphenol found in green tea that has been shown to inhibit certain protein kinases. This inhibition can shift the balance of cellular signaling to pathways in which WBSCR17 is active, thus enhancing its function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a specific inhibitor of phosphoinositide 3-kinases (PI3K). By inhibiting PI3K, LY294002 could lead to activation of alternate signaling pathways that enhance the activity of WBSCR17. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is another potent and specific inhibitor of PI3K. Similar to LY294002, wortmannin’s inhibition of PI3K may indirectly enhance WBSCR17 activity by affecting interconnected signaling pathways. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
A23187 is a calcium ionophore that increases intracellular calcium levels, which can activate calcium-dependent signaling pathways. These pathways may enhance the activity of WBSCR17 by promoting calcium-mediated cellular responses. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
Sphingosine-1-phosphate is a bioactive lipid that activates sphingosine-1-phosphate receptors, triggering signaling pathways that can enhance WBSCR17 activity through lipid signaling-mediated processes. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin is a SERCA pump inhibitor that leads to an increase in cytosolic calcium. Elevated calcium can activate various calcium-dependent kinases and phosphatases, potentially enhancing WBSCR17 activity. | ||||||