VibH Activators
VibH activators, in the context of this selection, cover a spectrum of cellular processes. Many of the listed chemicals affect second messengers or specific cellular kinases, emphasizing the interconnectedness of cellular signaling. For example, A23187 elevates intracellular calcium concentrations, a universal cellular messenger that influences myriad kinases and subsequent downstream proteins. Such a rise in calcium concentration could, in turn, impact proteins like VibH if they lie downstream of calcium-activated processes.
On the other hand, molecules like BAY 11-7082 show how cellular signaling is not merely about activation but also modulation. Inhibition of certain pathways, like the NF-κB pathway by BAY 11-7082, can lead to alterations in associated processes, indirectly influencing proteins like VibH. Similarly, Bisindolylmaleimide I, a PKC, reveals the importance of phosphorylation in cellular signaling. Altering the dynamics of kinases, such as PKC, can have ripple effects, influencing associated proteins and pathways. The modulating of Fenofibrate, a PPARα agonist, and Okadaic Acid, a PP2A, further emphasize the intricate web of cellular processes. Each activator's specific mode of action, whether through altering calcium dynamics, influencing kinase activities, or modulating receptor responses, demonstrates the vast landscape of cellular signaling and the influence on proteins like VibH.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
A calcium ionophore that increases intracellular calcium concentrations. Elevated calcium can activate various kinases and potentially influence downstream proteins like VibH. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
Inhibitor of NF-κB activation, which might lead to downstream effects on proteins, potentially affecting VibH if in the same pathway. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $105.00 $242.00 | 36 | |
PKC inhibitor that can modify PKC-dependent pathways, indirectly affecting proteins associated with this cascade, including VibH. | ||||||
Celastrol, Celastrus scandens | 34157-83-0 | sc-202534 | 10 mg | $158.00 | 6 | |
A proteasome modulator. By affecting proteasomal degradation, it can indirectly influence protein levels and their associated pathways, like VibH. | ||||||
Desmopressin | 16679-58-6 | sc-391126 | 1 mg | $138.00 | ||
Vasopressin receptor agonist which can activate various second messenger systems, potentially modulating VibH downstream. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $41.00 | 9 | |
PPARα agonist. By modulating peroxisome proliferator-activated receptors, it can influence related pathways potentially containing VibH. | ||||||
1-Oleoyl-2-acetyl-sn-glycerol (OAG) | 86390-77-4 | sc-200417 sc-200417A | 10 mg 50 mg | $119.00 $453.00 | 1 | |
DAG analog that activates protein kinase C, potentially modulating cascades including VibH downstream. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
PP2A inhibitor, affecting phosphorylation levels in cells. This modulation can influence signaling pathways containing VibH. | ||||||
PD 169316 | 152121-53-4 | sc-204168 sc-204168A sc-204168B sc-204168C | 1 mg 5 mg 10 mg 25 mg | $88.00 $156.00 $281.00 $461.00 | 3 | |
p38 MAPK inhibitor. By affecting the MAPK pathway, it can lead to alterations in proteins downstream, like VibH. | ||||||
Rottlerin | 82-08-6 | sc-3550 sc-3550B sc-3550A sc-3550C sc-3550D sc-3550E | 10 mg 25 mg 50 mg 1 g 5 g 20 g | $84.00 $166.00 $302.00 $2091.00 $5212.00 $16657.00 | 51 | |
Identified as a PKCδ inhibitor, and its modulation of PKCδ activity can influence related pathways potentially housing VibH. | ||||||