Date published: 2026-1-7

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Desmopressin (CAS 16679-58-6)

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Alternate Names:
1-Deamino-8-D-arginine vasopressin
Application:
Desmopressin is a synthetic vasopressin analog
CAS Number:
16679-58-6
Molecular Weight:
1069.22
Molecular Formula:
C46H64N14O12S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Desmopressin is a chemical analogue of the hormone vasopressin, and it is widely used in research to explore the regulation of water balance and memory processes. Its primary research application lies in the study of vasopressin receptors, where it acts as an agonist, particularly at the V2 receptor subtype located in the kidney. By binding to these receptors, desmopressin helps scientists understand the molecular pathways involved in water reabsorption. Additionally, researchers utilize desmopressin in genetic studies to investigate mutations in the vasopressin receptor gene and their impacts on renal function and behavior.


Desmopressin (CAS 16679-58-6) References

  1. Desmopressin and antifibrinolytics.  |  Horrow, JC. 1990. Int Anesthesiol Clin. 28: 230-6. PMID: 2228279
  2. Desmopressin in the treatment of nocturia: clinical evidence and experience.  |  Friedman, FM. and Weiss, JP. 2013. Ther Adv Urol. 5: 310-7. PMID: 24294289
  3. Desmopressin in adult urological disease: clinical evidences.  |  Siracusano, S., et al. 2015. Urologia. 82: 206-10. PMID: 26541674
  4. Desmopressin effectiveness in renal colic pain management: Systematic review and meta-analysis.  |  Jalili, M., et al. 2016. Am J Emerg Med. 34: 1535-41. PMID: 27289437
  5. Desmopressin for treatment of platelet dysfunction and reversal of antiplatelet agents: a systematic review and meta-analysis of randomized controlled trials.  |  Desborough, MJ., et al. 2017. J Thromb Haemost. 15: 263-272. PMID: 27893176
  6. Desmopressin acetate nasal spray for adults with nocturia.  |  Cohn, JA., et al. 2017. Expert Rev Clin Pharmacol. 10: 1281-1293. PMID: 29048257
  7. Desmopressin for treating nocturia in men.  |  Han, J., et al. 2017. Cochrane Database Syst Rev. 10: CD012059. PMID: 29055129
  8. Pediatric Pharmacology of Desmopressin in Children with Enuresis: A Comprehensive Review.  |  Gasthuys, E., et al. 2020. Paediatr Drugs. 22: 369-383. PMID: 32507959
  9. Use of Desmopressin in Hyponatremia: Foe and Friend.  |  Achinger, SG. and Ayus, JC. 2019. Kidney Med. 1: 65-70. PMID: 32734186
  10. Desmopressin treatment for nocturia caused by nocturnal polyuria: practical guidelines.  |  Przydacz, M., et al. 2020. Cent European J Urol. 73: 498-505. PMID: 33552576
  11. Desmopressin acetate the first sublingual tablet to treat nocturia due to nocturnal polyuria.  |  Alford, N. and Hashim, H. 2021. Expert Rev Clin Pharmacol. 14: 939-954. PMID: 33993824
  12. Desmopressin therapy in children and adults: pharmacological considerations and clinical implications.  |  Chin, X., et al. 2022. Eur J Clin Pharmacol. 78: 907-917. PMID: 35199198

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Desmopressin, 1 mg

sc-391126
1 mg
$138.00