1-Oleoyl-2-acetyl-sn-glycerol (OAG) CAS: 86390-77-4
MF: C23H42O5
MW: 398.6
A protein kinase C activating diacylglycerol.

1-Oleoyl-2-acetyl-sn-glycerol (OAG) (CAS 86390-77-4)

1-Oleoyl-2-acetyl-sn-glycerol (OAG) | CAS 86390-77-4 is rated 5.0 out of 5 by 1.
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Alternate Names: 1-O-9Z-octadecenoyl-2-O-acetyl-sn-glycerol; OAG
Application: 1-Oleoyl-2-acetyl-sn-glycerol (OAG) is a protein kinase C activating diacylglycerol
CAS Number: 86390-77-4
Purity: ≥90%
Molecular Weight: 398.6
Molecular Formula: C23H42O5
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

1-Oleoyl-2-acetyl-sn-glycerol (OAG) is a synthetic, membrane-permeable diacylglycerol analog demonstrated to activate PKC (Ca2+-dependent protein kinase C).


References

1. Kaibuchi, K., et al. 1983. J. Biol. Chem. 258: 6701-6704. PMID: 6406488
2. Barber, L.A. and Vasko, M.R. 1996. J. Neurochem. 67: 72-80. PMID: 8667028
3. Wang, R., et al. 1998. J. Immunol. 161: 2201-2207. PMID: 9725212
4. Saito, Y., et al. 1998. Mol. Cell. Endocrinol. 146: 197-205. PMID: 10022777
5. Thebault, S., et al. 2005. J. Cell. Physiol. 204: 320-328. PMID: 15672411

Formulation :
Solution in acetonitrile
Physical State :
Liquid
Solubility :
Soluble in DMSO, and ethanol (20 mg/ml).
Storage :
Store at -80° C
Boiling Point :
81.6° C
Refractive Index :
n20D 1.47 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Transport :
UN 1648, Class 3, Packing group II
PubChem CID :
6437055
MDL Number :
MFCD00166985
Beilstein Registry :
8168731
SMILES :
CCCCCCCC/C=C\CCCCCCCC(=O)OC[[email protected]](CO)OC(=O)C

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Bista Bista, P. et al. (PubMed 25556792) demonstrated that the inhibition of TASK channels is induced by the application of the DAG analogue and protein kinase C activating diacylglycerol 1-oleoyl-2-acetyl-sn-glycerol (OAG). -SCBT Publication Review
Date published: 2015-02-07
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