USF-1 Activators
USF-1 activators belong to a specific chemical class of compounds that are designed to modulate the activity of a transcription factor known as Upstream Stimulatory Factor 1 (USF-1). USF-1 is a critical transcription factor involved in the regulation of gene expression, playing a pivotal role in various cellular processes such as cell growth, differentiation, and apoptosis. These activators are characterized by their ability to interact with USF-1 and influence its function, ultimately impacting the transcription of target genes.
USF-1 activators can exert their effects through various mechanisms. Some compounds may enhance the binding of USF-1 to its target DNA sequences, promoting the transcription of specific genes. Others may inhibit the interaction of USF-1 with co-factors or suppress its transcriptional activity, leading to the downregulation of gene expression. These compounds are valuable tools in molecular biology and cellular research, allowing scientists to manipulate gene expression patterns and study the intricate regulatory networks within cells. Understanding the mechanisms of USF-1 activation or inhibition by these compounds can provide valuable insights into the fundamental biology of gene regulation and may have implications in various fields, although such applications should be carefully explored and validated through further research.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
It can increase cAMP levels, which may enhance USF-1 expression by activating protein kinase A (PKA) signaling pathways. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
This metabolite of vitamin A can regulate gene expression and potentially increase USF-1 expression. | ||||||
L-3,3′,5-Triiodothyronine, free acid | 6893-02-3 | sc-204035 sc-204035A sc-204035B | 10 mg 100 mg 250 mg | $40.00 $75.00 $150.00 | ||
A thyroid hormone that can influence USF-1 expression through thyroid hormone response elements in gene promoters. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $42.00 $62.00 $153.00 $255.00 $500.00 $30.00 | 37 | |
This compound activates AMPK, which may subsequently influence USF-1 transcription activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Known to activate SIRT1, which may indirectly enhance USF-1 expression through deacetylation mechanisms. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
It is a PPARγ agonist that may upregulate USF-1 expression as part of adipogenesis regulatory pathways. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This DNA methyltransferase inhibitor can alter gene expression patterns, potentially affecting USF-1 levels. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
As an HDAC inhibitor, it can modify chromatin structure and increase transcription of certain genes, including USF-1. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
This green tea polyphenol may modulate several signaling pathways, possibly influencing USF-1 expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
As a phytoestrogen, it may interact with estrogen receptors, influencing gene expression profiles such as USF-1. | ||||||