Date published: 2025-10-22

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TSG-6 Inhibitors

Common TSG-6 Inhibitors include, but are not limited to 2-Methoxyestradiol CAS 362-07-2, Curcumin CAS 458-37-7, Dimethyloxaloylglycine (DMOG) CAS 89464-63-1, Lovastatin CAS 75330-75-5 and Methotrexate CAS 59-05-2.

TSG-6 inhibitors are a group of chemical compounds that are designed to interact with and modulate the activity of Tumor necrosis factor-inducible gene 6 protein (TSG-6). TSG-6 is a multifunctional protein that is involved in various biological processes, including inflammation, tissue remodeling, and cell migration. These inhibitors are developed to target specific binding sites or interactions of TSG-6 with other proteins, molecules, or cellular structures.

By targeting TSG-6, these inhibitors provide a means to study and manipulate the complex network of signaling pathways and interactions in which TSG-6 participates. This allows researchers to explore the roles of TSG-6 in mediating inflammation, tissue repair, and other physiological processes. Studying the effects of TSG-6 inhibitors may offer insights into the intricate molecular mechanisms underlying inflammation-related conditions and their impact on cellular behavior. Overall, TSG-6 inhibitors serve as valuable tools for dissecting the functional roles of TSG-6 in various biological contexts and shedding light on its contribution to cellular and molecular processes.

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Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

2-Methoxyestradiol

362-07-2sc-201371
sc-201371A
10 mg
50 mg
$70.00
$282.00
6
(1)

Suppresses TSG-6 expression by interfering with its transcription.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Downregulates TSG-6 production by inhibiting its gene expression.

PX-478

685898-44-6sc-507409
10 mg
$175.00
(0)

Induces degradation of HIF-1α, a transcriptional regulator of TSG-6.

Dimethyloxaloylglycine (DMOG)

89464-63-1sc-200755
sc-200755A
sc-200755B
sc-200755C
10 mg
50 mg
100 mg
500 mg
$82.00
$295.00
$367.00
$764.00
25
(2)

Inhibits TSG-6 expression by stabilizing HIF-1α and impacting its regulation.

Lovastatin

75330-75-5sc-200850
sc-200850A
sc-200850B
5 mg
25 mg
100 mg
$28.00
$88.00
$332.00
12
(1)

Reduces TSG-6 production by affecting its upstream regulatory pathways.

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$92.00
$209.00
33
(5)

Inhibits TSG-6 expression through its anti-inflammatory effects.

Kaempferol

520-18-3sc-202679
sc-202679A
sc-202679B
25 mg
100 mg
1 g
$97.00
$212.00
$500.00
11
(1)

Downregulates TSG-6 expression by affecting its gene transcription.

Celastrol, Celastrus scandens

34157-83-0sc-202534
10 mg
$155.00
6
(1)

Suppresses TSG-6 levels by impacting its regulatory pathways.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$88.00
$200.00
13
(1)

Inhibits TSG-6 expression through modulation of regulatory pathways.

15-Deoxy-δ12,14-Prostaglandin J2

87893-55-8sc-201262
sc-201262A
1 mg
5 mg
$138.00
$540.00
5
(1)

Downregulates TSG-6 expression through its anti-inflammatory effects.