TSG-6 Activators

Common TSG-6 Activators include, but are not limited to Lipopolysaccharide, E. coli O55:B5 CAS 93572-42-0, PMA CAS 16561-29-8, Hyaluronic acid CAS 9004-61-9, Zymosan CAS 9010-72-4 and Resveratrol CAS 501-36-0.

TSG-6 (Tumor Necrosis Factor-Stimulated Gene-6) is a multifunctional protein involved in inflammation and tissue remodeling. Its expression can be induced by various pro-inflammatory mediators, and it plays roles in processes such as matrix remodeling, cell migration, and inflammation resolution. TSG-6 (Tumor Necrosis Factor-Stimulated Gene 6) Activators represent a class of chemical compounds that can influence the activity of the TSG-6 protein. TSG-6 is a multifunctional protein involved in various physiological processes, primarily associated with inflammation and tissue remodeling. It belongs to the hyaluronan-binding protein family and is characterized by its ability to interact with hyaluronan, a large polysaccharide present in the extracellular matrix. TSG-6 plays a crucial role in regulating inflammatory responses and tissue repair, making it a valuable target for research aimed at understanding these processes.

Activation of TSG-6 typically involves various signaling pathways and post-translational modifications, although the specific mechanisms are still an active area of study. This protein is recognized for its anti-inflammatory properties, particularly its ability to inhibit neutrophil migration and reduce pro-inflammatory cytokine production. Additionally, TSG-6 is known to modulate the interaction between leukocytes and the extracellular matrix, contributing to tissue repair and remodeling. Researchers studying TSG-6 Activators aim to uncover the intricate details of how these compounds influence TSG-6 function, which in turn can provide valuable insights into the regulation of inflammation and tissue repair mechanisms in various physiological and pathological contexts.