Trimethyl Arg Asymmetric Inhibitors
Trimethyl Arg Asymmetric Inhibitors comprise a diverse array of compounds that impede the enzymatic activity or expression of proteins involved in the asymmetric trimethylation of arginine residues. These inhibitors target various cellular processes, including methylation reactions, signaling pathways, and gene expression mechanisms, thereby influencing the function of Trimethyl Arg Asymmetric. For instance, compounds like sinefungin and adenosine interfere with methyltransferase enzymes and methyl donor availability, respectively, disrupting the methylation of arginine residues and affecting Trimethyl Arg Asymmetric.
Furthermore, inhibitors such as ralimetinib and IWP-2 target signaling pathways like JAK/STAT and Wnt, respectively, which regulate the expression or activity of proteins involved in arginine methylation. By modulating these pathways, these inhibitors can indirectly influence the function of Trimethyl Arg Asymmetric. Additionally, compounds like ribavirin and streptonigrin exert their effects by disrupting cellular processes such as RNA metabolism and inducing DNA damage and apoptosis, which may alter the cellular environment and impact Trimethyl Arg Asymmetric function. Overall, Trimethyl Arg Asymmetric Inhibitors represent a valuable tool for investigating the role of arginine methylation in cellular physiology.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sinefungin | 58944-73-3 | sc-203263 sc-203263B sc-203263C sc-203263A | 1 mg 100 mg 1 g 10 mg | $266.00 $5100.00 $39576.00 $690.00 | 4 | |
Sinefungin inhibits methyltransferase enzymes, including those involved in trimethylation of arginine residues. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $33.00 $47.00 $294.00 $561.00 $1020.00 $2550.00 $4590.00 | 1 | |
Adenosine competes with S-adenosylmethionine (SAM), a methyl donor, thereby inhibiting arginine methylation reactions. | ||||||
Ribavirin | 36791-04-5 | sc-203238 sc-203238A sc-203238B | 10 mg 100 mg 5 g | $62.00 $108.00 $210.00 | 1 | |
Ribavirin interferes with RNA metabolism, potentially disrupting the expression or function of Trimethyl Arg Asymmetric. | ||||||
Amodiaquine | 86-42-0 | sc-207282 | 10 mg | $342.00 | 1 | |
Amodiaquine inhibits protein arginine methyltransferases (PRMTs), enzymes responsible for arginine methylation. | ||||||
LY2228820 | 862507-23-1 | sc-364525 | 5 mg | $191.00 | 1 | |
Ralimetinib inhibits JAK1 and JAK2, downstream kinases involved in signaling pathways that regulate protein methylation. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol inhibits PRMTs and disrupts the methylation of arginine residues in proteins, potentially inhibiting Trimethyl Arg Asymmetric. | ||||||
Streptonigrin | 3930-19-6 | sc-500892 sc-500892A | 1 mg 5 mg | $102.00 $357.00 | 1 | |
Streptonigrin induces DNA damage and apoptosis, potentially affecting cellular processes regulated by Trimethyl Arg Asymmetric. | ||||||
6-Thioguanine | 154-42-7 | sc-205587 sc-205587A | 250 mg 500 mg | $41.00 $53.00 | 3 | |
NG-Hydroxy-L-arginine competes with arginine for the active site of PRMTs, inhibiting their enzymatic activity. | ||||||
Chlorzoxazone | 95-25-0 | sc-211078 | 10 mg | $61.00 | ||
Chlorzoxazone inhibits PRMT5, a major protein arginine methyltransferase, potentially affecting Trimethyl Arg Asymmetric. | ||||||
IWP-2 | 686770-61-6 | sc-252928 sc-252928A | 5 mg 25 mg | $94.00 $286.00 | 27 | |
IWP-2 inhibits the Wnt signaling pathway, which is involved in regulating gene expression, including that of PRMTs. | ||||||