Molecular structure of Adenosine, CAS Number: 58-61-7
Adenosine (CAS 58-61-7)
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Alternate Names:
9-β-D-Ribofuranosyladenine; Adenine riboside; Adenine-9-β-D-ribofuranoside
Application:
Adenosine is an apoptosis inducer and an Adenosine A Receptor activator
CAS Number:
58-61-7
Purity:
≥99%
Molecular Weight:
267.24
Molecular Formula:
C10H13N5O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Adenosine, a purine-based compound present in all living organisms, holds a position. It constitutes a nucleoside, formed by the combination of adenine and ribose, and serves as a vital component of adenosine triphosphate (ATP), the molecule responsible for energy production. Functioning across numerous cellular processes, adenosine assumes a significant role in gene expression regulation, energy metabolism, and cell signaling. In vitro experimentation relies on adenosine to investigate the impact of drugs on cells and tissues. Acting as a ligand, adenosine interacts with several receptors, including A1, A2A, A2B, and A3 receptors. The binding of adenosine to these receptors initiates diverse cellular responses, such as neurotransmitter release, ion channel activation, and gene expression regulation.
Adenosine (CAS 58-61-7) References
- Adenosine inhibits IL-12 and TNF-[alpha] production via adenosine A2a receptor-dependent and independent mechanisms. | Haskó, G., et al. 2000. FASEB J. 14: 2065-74. PMID: 11023991
- Influence of inhibition of adenosine uptake on the gamma-aminobutyric acid level of the ischemic rat brain. | Seif-el-Nasr, M. and Khattab, M. 2002. Arzneimittelforschung. 52: 353-7. PMID: 12087919
- Highly sensitive method for the determination of adenosine by LC-MS/MS-ESI: method validation and scope of application to a pharmacokinetic/pharmacodynamic study. | Sharma, K., et al. 2012. Biomed Chromatogr. 26: 81-8. PMID: 21491472
- Untargeted metabolomics reveals a mild impact of remote ischemic conditioning on the plasma metabolome and α-hydroxybutyrate as a possible cardioprotective factor and biomarker of tissue ischemia. | Laursen, MR., et al. 2017. Metabolomics. 13: 67. PMID: 28473744
- Visualizing Dynamics of Cell Signaling In Vivo with a Phase Separation-Based Kinase Reporter. | Zhang, Q., et al. 2018. Mol Cell. 69: 334-346.e4. PMID: 29307513
- 1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors. | Daly, JW., et al. 1985. J Med Chem. 28: 487-92. PMID: 2984420
- Functionalized congeners of 1,3-dialkylxanthines: preparation of analogues with high affinity for adenosine receptors. | Jacobson, KA., et al. 1985. J Med Chem. 28: 1334-40. PMID: 2993622
- FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle. | Cader, MZ., et al. 2020. Cell. 180: 278-295.e23. PMID: 31978345
- N6-methyladenosine (m6A) is an endogenous A3 adenosine receptor ligand. | Ogawa, A., et al. 2021. Mol Cell. 81: 659-674.e7. PMID: 33472058
- Potential and promising anticancer drugs from adenosine and its analogs. | Man, S., et al. 2021. Drug Discov Today. 26: 1490-1500. PMID: 33639248
- Comparison of metabolism substances in Cordyceps sinensis and Cordyceps militaris cultivated with tussah pupa based on LC-MS. | Liu, Y., et al. 2021. J Food Biochem. 45: e13735. PMID: 33890309
- Adenosine deaminase 2 produced by infiltrative monocytes promotes liver fibrosis in nonalcoholic fatty liver disease. | Tiwari-Heckler, S., et al. 2021. Cell Rep. 37: 109897. PMID: 34706243
- Therapeutic effects of Chinese medicine Di-Long (Pheretima vulgaris) on rheumatoid arthritis through inhibiting NF-κB activation and regulating Th1/Th2 balance. | Bao, Y., et al. 2022. Biomed Pharmacother. 147: 112643. PMID: 35033948
- Liquid chromatography method for simultaneous quantification of ATP and its degradation products compatible with both UV-Vis and mass spectrometry. | Law, AS., et al. 2022. J Chromatogr B Analyt Technol Biomed Life Sci. 1206: 123351. PMID: 35797802
Inhibitor of:
ADAT1, AHCYL1, AHCYL2, AKAP 2, AKAP 3, AP4A Hydrolase, biotinidase, cAMP-GEFII, CARM1, CNT1, DDX16, DHX32, GAMT, GPR83, ICF45, MAT IIα, Olfr972, Olr242, ORCTL2, PCMTD1, PHGR1, PKA IIβ reg, PRMT7, PRPS1, SAHH-3, SATL1, SULT1A4, Trimethyl Arg Asymmetric, TRM12, V1RB4, and VPAC2.Activator of:
β-1,4-Gal-T2, δ-sarcoglycan, γ-GCSc, 1700034O15Rik, 2′-PDE, 2610528A11Rik, 2610528E23Rik, 4933406M09Rik, 4933425L06Rik, 5′-nucleotidas, 5′-nucleotidase, A530099J19Rik, ACADS, ACY1L2, Adad2, ADAT2, Adducin α, Adenosine A1-R, Adenosine A2A-R, adenosine deaminase, ADK, ADM Receptor, ADSL, AGAT, AGS3, AK1, AK3, AKAP 1, AKAP 13, AKAP 149_AKAP 121, AKAP 79, ALOXE3, AMPD1, AMPD3, Angptl1, ANKRD23, Annexin A10, ART2A, ART5, Atase, Blr1, C11orf70, C130060K24Rik, C20orf152, CALHM1, CCDC84, CD300C, CD39L1, CD73, CD88, CD97, Cdc35, Cdc7, CECR5, Centrin-4, Chromozym X, CKR-8, CMPK, CNT1, CNT2, CNT3, COMMD6, COMT, CRE-BPa, CREBRF, CXX1, Cya A, CYP11B1, Cypin, CYTL1, DANGER, DAPK, Dbf4, dCK, DDX35, DNAH12, Dok-1, Duffy, Dyrk3, EG628518, EG667472, ENDOD1, ENT2, ENT3, ENT4, eotaxin-3, ETL, Factor XIII A, FAM13b, FBXO44, G α o, Gα 14, Gα 15, Gα gust, Gα z, Gβ 3, Gγ 10, Gγ 11, Gγ 13, Gγ 5, GAIP, GALK2, GART, GASP-1, GBF1, Genethonin-1, Glucagon Receptor, Glut5, Glycophorin D, Gm14496, GNB1L, GNGT2, GNPTAB, GOLGA8A, GOLGA8R, GP2, GPR-137, GPR-152, GPR1, GPR105, GPR107, GPR112, GPR135, GPR141, GPR148, GPR149, GPR155, GPR158, GPR17, GPR176, GPR19, GPR20, GPR26, GPR32, GPR4, GPR61, GPR78, GPR80, GPR84, GPR89, GRK 1, GRK 4, GRK 5, GRO1, HARBI1, hCG_40738, Hex, HISPPD2A, HNK-1ST, HPRT, HS2ST1, HTF9C, I-309, IL-13Rα2, IL-7R, ISLR2, Junctophilin-2, KCNE4, KIAA1429, KIAA2018, KIF13B, KIF1A, KIF21B, KIR2.2, Kir3, KIR3.1, KIR3.2, KIR3.3, KLHL26, KRTAP2-4, KRTAP4-4, KRTAP5-2, KRTAP5-6, KRTAP7-1, L7RN6, LCMT1, LOC257407, LOC401317, LOC646457, LTH-A, Ly-6D, MAT Iα, MAT IIβ, Med29, MIP-1b, MPND, MrgA4, MrgA8, MS4A12, MS4A13, MS4A3, MS4A6A, MTR, NBL4, NCBE, nephrocystin-2, Neurexophilin-4, NMBR, Nph1, NPS, NSUN2, NT5C3, Obp1b, Olfr1009, Olfr1012, Olfr1054, Olfr1061, Olfr1079, Olfr1085, Olfr1094, Olfr1095, Olfr1274, Olfr1458, Olfr3, Olfr303, Olfr328, Olfr329, Olfr362, Olfr365, Olfr366, Olfr367, Olfr368, Olfr370, Olfr390, Olfr467, Olfr514, Olfr814, Olfr815, Olfr816, Olfr818, Olfr820, Olfr821, Olfr822, Olfr823, Olr1020, Olr104, Olr1059, Olr1061, Olr1104, Olr242, Olr25, Olr252, Olr257, Olr264, Olr27, Olr272, Olr286, Olr3, Olr309, Olr322, Olr336, Olr348, Olr357, Olr363, Olr37, Olr375, Olr390, Olr400, Olr402, Olr403, Olr408, Olr410, Olr415, Olr419, Olr421, Olr434, Olr440, Olr444, Olr480, Olr483, Olr490, Olr500, Olr515, Olr517, Olr530, Olr540, Olr542, Olr554, Olr557, Olr560, Olr569, Olr577, Olr598, Olr607, Olr610, Olr614, Olr63, Olr636, Olr649, Olr655, Olr659, Olr668, Olr684, Olr694, Olr697, Olr707, Olr713, Olr714, Olr72, Olr726, Olr728, Olr734, Olr74, Olr744, Olr748, OR10A5, OR10G3, OR10S1, OR13F1, OR2A1, OR2A12, OR2C1, OR3A1, OR3A3, OR4A15, OR4A16, OR4C13, OR4C3, OR4C46, OR4D9, OR4K17, OR4N4, OR4P4, OR4X1, OR56A4, OR5AC2, OR5AP2, OR5AR1, OR5AS1, OR5AU1, OR5F1, OR6C2, OR6C4, OR6C65, OR6C70, OR6C75, OR7A10, OR7G1, OR7G2, OR8B12, OR8B3, OR8H3, OR9A4, OR9G1, OR9G4, OR9K2, OR9Q2, OSGEPL1, OTTMUSG00000003947, OTTMUSG00000004010, OTTMUSG00000016321, OX2, OX2R, P protein, P2X5, PANK1, PAPST1, PATJ, PCIF1, PDE4A, PDE7B, PDE8B, PGP-I, Pgr15l, PHACTR2, phospholemman, PHT2, PIA, PIB, Pigr, PIMT, PIR1, pki β, Platelet IIb, PLC ε2, PLC η1, PLEKHH2, PNP, POLDIP3, PRMT1, PRMT8, Pronase, PSG7, PTRF, Punc, Rab 3C, Rap 2C, Rap1GAP, RBKS, RBPMS2, REP15, RERGL, RFPL4, RFPL4B, RG9MTD2, RGS4, RIBC1, RIC-8B, RIMBP3C, RmlB, RRS1, RTP4, SAHH, SAHH-3, Sar1a, SC, SIGLECL1, SIRP-β1, SIT, SLC17A4, SLC22A14, Slc5a11, SMC6, SMOC-2, SMYD1, sodium/potassium-ATPase β1, SorCS1, SREB1, SRP14, SSH2, STOP, SULT2A3, SULT2A6, Synapsin IIIa, TARC, TASK-2, TBCEL, TCP-c, TDAG8, Tect1, TG1019, TIP20, TM4-B, TMEFF1, TMEM132A, TPSB2, TPSB3, TPST-2, Tra-2α, Transaldolase, Tryptase, TSEN34, TTC17, TTC33, UPase, UT-B, V1RA1, V1RA6, V1RA8, V1RB4, V1RC10, V1RC26, V1RC28, V1RD13, V1RD15, V1RD17, V1RD19, V1RD20, V1RD6, V3R 1, VAMP-3, Visual Arrestin, Vmn1r114, Vmn1r124, Vmn1r142, Vmn1r143, Vmn1r161, Vmn1r169, Vmn1r224, Vmn2r105, Vmn2r12, Vmn2r122, Vmn2r2, Vmn2r29, Vmn2r6, Vmn2r60, Vmn2r62, Vmn2r63, Vmn2r65, Vmn2r66, Vmn2r67, Vmn2r68, Vmn2r69, Vmn2r7, Vmn2r71, Vmn2r73, Vmn2r75, Vmn2r77, Vmn2r79, Vmn2r81, Vmn2r83, WDR89, XLαs, YTHDF1, and YTHDF3.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Adenosine, 1 g | sc-291838 | 1 g | $33.00 | |||
Adenosine, 5 g | sc-291838A | 5 g | $47.00 | |||
Adenosine, 100 g | sc-291838B | 100 g | $294.00 | |||
Adenosine, 250 g | sc-291838C | 250 g | $561.00 | |||
Adenosine, 1 kg | sc-291838D | 1 kg | $1020.00 | |||
Adenosine, 5 kg | sc-291838E | 5 kg | $2550.00 | |||
Adenosine, 10 kg | sc-291838F | 10 kg | $4590.00 |