TRIM34 Activators
TRIM34 activators represent a class of chemical compounds designed to modulate the activity of the TRIM34 protein, also known as Tripartite Motif-Containing 34. TRIM34 is a member of the TRIM family of proteins, characterized by the presence of a tripartite motif consisting of a RING finger domain, one or two B-box domains, and a coiled-coil region. These proteins are involved in various cellular processes, including immunity, antiviral defense, and regulation of protein degradation.
TRIM34 activators are specifically engineered to interact with TRIM34 and influence its molecular functions. While the precise functions of TRIM34 are still being elucidated, it has been implicated in processes such as antiviral immunity and protein degradation through ubiquitination. By targeting TRIM34, these compounds may modulate its role in specific cellular pathways, affecting immune responses or protein turnover. The study of TRIM34 activators provides insights into the complex mechanisms of protein regulation and cellular defense mechanisms, contributing to a deeper understanding of the molecular basis of cellular responses to pathogens and the control of protein homeostasis. Further research is needed to unravel the precise mechanisms of action and biological consequences associated with TRIM34 activation, with implications for understanding the broader context of innate immunity and cellular protein quality control.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Polyinosinic acid - polycytidylic acid sodium salt, double-stranded | 42424-50-0 | sc-204854 sc-204854A | 10 mg 100 mg | $139.00 $650.00 | 2 | |
Poly(I:C) is a synthetic analog of double-stranded RNA and is a potent immune stimulant. It might induce the expression of antiviral proteins, including TRIM34. | ||||||
Imiquimod | 99011-02-6 | sc-200385 sc-200385A | 100 mg 500 mg | $66.00 $278.00 | 6 | |
Imiquimod is an immune response modifier. Given its role in boosting antiviral defenses, it might influence TRIM34 expression. | ||||||
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $96.00 $166.00 $459.00 $1615.00 | 12 | |
LPS stimulates the innate immune response and could potentially upregulate antiviral proteins like TRIM34. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin has broad effects on cellular signaling and inflammation. Its influence on immune pathways might modulate TRIM34 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol modulates various cellular pathways, including immune responses. It might influence the expression of TRIM34. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
As a DNA methyltransferase inhibitor, 5-Azacytidine can modulate gene expression, potentially influencing the expression of immune-related genes like TRIM34. | ||||||
Adapalene | 106685-40-9 | sc-203803 sc-203803A | 10 mg 50 mg | $65.00 $325.00 | 2 | |
TGF-beta can modulate immune responses. Its signaling might influence the expression of proteins like TRIM34. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Etoposide induces DNA damage and can activate immune pathways, potentially influencing TRIM34 expression. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Bortezomib affects proteasome activity and can modulate immune responses, potentially influencing TRIM34 expression. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
JQ1 affects the BRD4 protein and influences gene expression. Its modulation of immune-related genes might include TRIM34. | ||||||