TRIM34 inhibitors are a class of chemical compounds designed to target and inhibit the activity of TRIM34, which is short for Tripartite Motif Containing 34. TRIM34 belongs to the family of TRIM proteins, characterized by their conserved tripartite motif (RING domain, B-box domain, and coiled-coil domain), and it plays various roles within the cellular environment. While the exact functions of TRIM34 are still under investigation, it is known to be involved in a range of cellular processes, including protein degradation, immune response, and the regulation of intracellular signaling pathways.
These inhibitors are valuable tools for researchers aiming to explore the functions and molecular interactions of TRIM34 in different cellular contexts. By selectively inhibiting TRIM34 activity, scientists can dissect its roles in processes like protein turnover and immune response regulation. Understanding TRIM34's functions and downstream targets can shed light on its involvement in cellular homeostasis and may uncover links to various diseases and conditions. The development of TRIM34 inhibitors is thus an important step in advancing our knowledge of this protein's roles and its significance in cellular biology and pathology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Known to inhibit protein synthesis in eukaryotic organisms by affecting the ribosomal function. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
A proteasome inhibitor that prevents protein degradation, potentially impacting TRIM34 levels indirectly. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Inhibits RNA synthesis which can lead to decreased protein expression. | ||||||
Mitoxantrone | 65271-80-9 | sc-207888 | 100 mg | $279.00 | 8 | |
An antineoplastic agent that intercalates DNA and can impact gene expression. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
Affects RNA processing and can inhibit protein synthesis. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent kinase inhibitor which might influence pathways regulating TRIM34 expression. | ||||||
Autophagy Inhibitor, 3-MA | 5142-23-4 | sc-205596 sc-205596A | 50 mg 500 mg | $56.00 $256.00 | 113 | |
PI3K inhibitor that might influence pathways associated with TRIM34 expression. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Another PI3K inhibitor with potential effects on protein expression pathways. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor which could influence transcription and translation processes. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, impacting downstream pathways that might influence TRIM34 expression. | ||||||