TMEM195 activators belong to a specialized class of compounds that target and increase the activity of the transmembrane protein 195 (TMEM195). TMEM195 is a protein whose functions and mechanisms of action within cellular processes remain largely enigmatic, though it has been identified as part of the transmembrane protein family, which suggests a role in cellular transport, signaling, or acting as a receptor or channel. As such proteins are fundamental components of cellular homeostasis and intercellular communication, activators of TMEM195 might enhance its natural function, potentially affecting the transport of molecules across the membrane or modulating signaling pathways in which TMEM195 is involved. These activators can work by various mechanisms, such as altering the protein's conformation to a more active state, facilitating its localization to the membrane, or promoting its interaction with other cellular proteins.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $41.00 | 9 | |
Fenofibrate is a fibric acid derivative that can activate peroxisome proliferator-activated receptor alpha (PPARα), potentially increasing the expression of enzymes involved in lipid metabolism like AGMO. | ||||||
Clofibrate | 637-07-0 | sc-200721 | 1 g | $33.00 | ||
Similar to fenofibrate, clofibrate is also a PPARα agonist which may enhance the transcription of genes involved in lipid processing, potentially including AGMO. | ||||||
WY 14643 | 50892-23-4 | sc-203314 | 50 mg | $136.00 | 7 | |
WY-14643 is a potent PPARα agonist, which could induce the expression of a range of genes involved in fatty acid metabolism, possibly affecting AGMO levels. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
As a PPARγ agonist, rosiglitazone can influence lipid metabolism and might indirectly upregulate the expression of lipid-metabolizing enzymes including AGMO. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $55.00 $125.00 | 13 | |
Pioglitazone, another PPARγ agonist, could similarly affect the expression of enzymes involved in lipid processing and potentially AGMO. | ||||||
Sodium phenylbutyrate | 1716-12-7 | sc-200652 sc-200652A sc-200652B sc-200652C sc-200652D | 1 g 10 g 100 g 1 kg 10 kg | $77.00 $166.00 $622.00 $5004.00 $32783.00 | 43 | |
4-Phenylbutyrate is a histone deacetylase inhibitor that can alter gene expression; it may upregulate enzymes responsible for lipid metabolism, including AGMO. | ||||||
Oleic Acid | 112-80-1 | sc-200797C sc-200797 sc-200797A sc-200797B | 1 g 10 g 100 g 250 g | $37.00 $104.00 $580.00 $1196.00 | 10 | |
Oleic acid, a monounsaturated fatty acid, could potentially alter lipid metabolic pathways and thus modulate the expression of related enzymes such as AGMO. | ||||||
T 0901317 | 293754-55-9 | sc-202824 sc-202824A | 10 mg 50 mg | $89.00 $224.00 | 5 | |
T0901317 is an agonist for liver X receptors (LXRs), which regulate the expression of genes involved in lipid metabolism and could potentially increase AGMO expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid influences gene expression through its action on retinoic acid receptors and may affect various metabolic pathways, potentially including AGMO transcription. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone can influence various metabolic processes and gene expression patterns; it might induce the expression of enzymes like AGMO as part of a wider metabolic adjustment. | ||||||