THAP9 Activators
THAP9 activators belong to a specialized chemical class recognized for their ability to modulate the activity of THAP9, a protein encoded by the THAP9 gene. THAP9, also known as Thanatos-associated protein 9, is a member of the THAP (Thanatos-associated protein) domain-containing family of proteins. While the precise function of THAP9 is still under investigation, studies suggest its involvement in various cellular processes, including transcriptional regulation, chromatin remodeling, and cell cycle progression. Activators targeting THAP9 exert their effects by potentially influencing its DNA-binding activity, protein-protein interactions, or subcellular localization. These activators play a crucial role in unraveling the biological functions of THAP9 and its contributions to cellular physiology.
Structurally, THAP9 activators may exhibit diverse chemical architectures, reflecting the complexity required for effective engagement with the target protein. These molecules may possess specific binding motifs or functional groups that facilitate their interaction with THAP9, enabling them to modulate its activity with precision. Understanding the structural and biochemical properties of THAP9 activators is essential for unraveling the molecular mechanisms underlying the functions of this protein and its involvement in cellular processes. Further exploration of the pharmacological characteristics and biological significance of THAP9 activators holds promise for advancing our understanding of cellular physiology and may offer insights into novel strategies for manipulating cellular functions in various biological contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
As a histone deacetylase inhibitor, TSA may enhance THAP9 expression by increasing chromatin accessibility for transcription. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that could upregulate THAP9 by demethylating DNA and activating gene transcription. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $45.00 | 5 | |
Might influence THAP9 expression through its role in enhancing histone demethylation, affecting gene expression. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
As a potent estrogen, β-Estradiol could modulate THAP9 expression through estrogen receptor-mediated transcriptional activation. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Could affect THAP9 expression by inhibiting mTOR signaling, involved in cell growth, proliferation, and transcriptional regulation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
May influence THAP9 expression through retinoid receptor-mediated signaling pathways involved in cell differentiation and apoptosis. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
Might modulate THAP9 expression by inhibiting NF-κB, affecting transcriptional regulation of genes involved in cell survival and apoptosis. | ||||||
Tyrphostin B42 | 133550-30-8 | sc-3556 | 5 mg | $26.00 | 4 | |
Could downregulate pathways that, when inhibited, lead to compensatory upregulation of transcription factors like THAP9. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Might influence THAP9 expression through the PI3K/Akt signaling pathway, affecting various transcriptional and cellular processes. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Could enhance THAP9 expression by altering chromatin structure and increasing transcriptional activity. | ||||||