THAP7 Activators
THAP7, or THAP domain-containing protein 7, is a member of the THAP (Thanatos-associated protein) domain protein family. The THAP proteins are characterized by the presence of a conserved DNA-binding domain known as the THAP domain, which is involved in transcriptional regulation and other cellular processes such as cell cycle control and apoptosis.The THAP7 protein specifically is implicated in the regulation of gene expression. It can act as a transcriptional repressor, modulating the expression of target genes by binding to specific DNA sequences. The THAP domain facilitates this interaction with DNA, enabling THAP7 to exert its regulatory effects within the cell nucleus.
In addition to its role in transcriptional regulation, THAP7, like other THAP domain proteins, may be involved in the maintenance of chromatin structure and the regulation of cell proliferation. However, the full range of its biological functions and the mechanisms by which it influences these processes are not entirely clear and may require further research to elucidate.The study of THAP7 and related proteins is significant because of their potential involvement in developmental processes and their dysregulation in diseases such as cancer. THAP proteins have been shown to interact with other factors involved in epigenetic regulation, suggesting that THAP7 may also play a role in modifying chromatin states and influencing gene expression patterns during development and in response to cellular signals.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor, can modify chromatin structure, potentially influencing THAP7-related pathways. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
A DNA methyltransferase inhibitor, can alter gene expression, potentially impacting THAP7 activity. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Another histone deacetylase inhibitor, may affect chromatin remodeling and thus THAP7 function. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
A short-chain fatty acid with histone deacetylase inhibitory activity, might influence THAP7. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Histone deacetylase inhibitor, can alter chromatin structure and gene expression, potentially impacting THAP7. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
An inhibitor of SP1 transcription factor, potentially affecting transcription factors like THAP7. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Influences cell differentiation and gene expression, potentially modulating THAP7 activity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A polyphenol that can modulate gene expression, potentially influencing THAP7. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
458-37-7 | A compound with various biological activities, including modulation of transcription factors and gene expression, potentially affecting THAP7. | | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
A polyphenolic compound known to influence gene expression and cellular signaling, possibly impacting THAP7. | ||||||