TEX101 inhibitors belong to a distinctive chemical class characterized by their ability to modulate the activity of TEX101, a glycoprotein prominently expressed in the testis. TEX101 itself plays a crucial role in the male reproductive system, specifically during spermatogenesis. Spermatogenesis is the intricate process of sperm cell development, and TEX101 is implicated in the interaction between sperm and Sertoli cells within the seminiferous tubules of the testis. These inhibitors function by selectively binding to TEX101, thereby altering its activity and subsequently influencing the intricate cellular interactions that underlie the maturation of sperm cells. The modulation of TEX101 activity by these inhibitors may have downstream effects on the regulation of immune responses and cellular adhesion events within the testicular microenvironment.
TEX101 inhibitors exhibit a specific molecular architecture tailored to interact with the binding sites of TEX101. This interaction disrupts the normal functioning of TEX101, potentially leading to altered cellular processes in the testis. The chemical class of TEX101 inhibitors encompasses a diverse range of compounds, each with its unique molecular features and binding affinities for TEX101. Researchers are actively exploring the structural nuances of these inhibitors to gain insights into the precise mechanisms through which they influence TEX101-mediated cellular events.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Suramin sodium | 129-46-4 | sc-507209 sc-507209F sc-507209A sc-507209B sc-507209C sc-507209D sc-507209E | 50 mg 100 mg 250 mg 1 g 10 g 25 g 50 g | $152.00 $214.00 $728.00 $2601.00 $10965.00 $21838.00 $41096.00 | 5 | |
Suramin is known to inhibit various growth factors and may disrupt cell communication mechanisms that TEX101 could be a part of. | ||||||
GW4869 | 6823-69-4 | sc-218578 sc-218578A | 5 mg 25 mg | $203.00 $611.00 | 24 | |
As a neutral sphingomyelinase inhibitor, GW4869 can affect sphingolipid metabolism, potentially impacting TEX101-related processes. | ||||||
Bisphenol A | 80-05-7 | sc-391751 sc-391751A | 100 mg 10 g | $300.00 $490.00 | 5 | |
Bisphenol A, an endocrine disruptor, can interfere with hormone signaling pathways, possibly affecting TEX101 function indirectly. | ||||||
PD 168393 | 194423-15-9 | sc-222138 | 1 mg | $162.00 | 4 | |
PD168393 is an irreversible EGFR inhibitor that may affect cellular pathways influencing TEX101 expression or function. | ||||||
Daidzein | 486-66-8 | sc-24001 sc-24001A sc-24001B | 100 mg 500 mg 5 g | $28.00 $79.00 $165.00 | 32 | |
Similar to genistein, daidzein is an isoflavone that can influence kinase signaling, potentially altering TEX101-related pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
As a PI3K inhibitor, LY294002 can modify intracellular signaling, which could affect the processes where TEX101 is involved. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 is a p38 MAPK inhibitor, which might modify inflammatory response and cell differentiation processes linked to TEX101. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is another PI3K inhibitor, potentially affecting signaling pathways that TEX101 could be involved in. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
As a JNK inhibitor, SP600125 can change the way cells respond to stress, which might indirectly influence TEX101's activity. | ||||||
Apocynin | 498-02-2 | sc-203321 sc-203321A sc-203321B sc-203321C | 1 g 10 g 100 g 500 g | $27.00 $68.00 $116.00 $360.00 | 74 | |
Apocynin is an inhibitor of NADPH oxidase, which could affect oxidative stress pathways and indirectly the role of TEX101. | ||||||