Molecular structure of PD 168393, CAS Number: 194423-15-9
PD 168393 (CAS 194423-15-9)
See product citations (4)
Alternate Names:
4-[(3-Bromophenyl)amino]-6-acrylamidoquinazoline
Application:
PD 168393 is a potent, cell-permeable, irreversible inhibitor of EGFR
CAS Number:
194423-15-9
Purity:
≥95%
Molecular Weight:
369.2
Molecular Formula:
C17H13BrN4O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
PD 168393 is a potent, irreversible, cell-permeable and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity. Does not inhibit any other protein kinases. PD 168393 binds to the catalytic domain of the EGFR with a 1:1 stoichiometry and alkylating Cys773.
PD 168393 (CAS 194423-15-9) References
Fry, D.W., et al. 1998. Proc. Natl. Acad. Sci USA 95, 12022.Inhibitor of:
ADAM39, AI449175, ARNO, BTF3, C230052I12Rik, CEACAM3, CRISP-2, EAT2, EFR3B, EGFL3, EGFR, EPHEXIN, FAM171B, FAPα, hCG_2040054, HPV16 E5, ILT-8, LERK-3, LOC729718, LRCH4, LRFN4, LYPD5, Myoneurin, NDG1, OR1J2, PCDGF, PCDHB, RUSC1, SAMC, TEX101, TMEM104, TSA-1, ZFP28, ZFPL1, ZNF146, ZNF284L, ZNF324B, ZNF333, ZNF37A, ZNF383, ZNF462, ZNF525, ZNF545, and ZNF565.Activator of:
C9orf23_2810432D09Rik, OR1Q1, RGNEF, and SHKBP1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PD 168393, 1 mg | sc-222138 | 1 mg | $162.00 |