TBL1Y activators refer to a diverse group of chemicals that target and promote the activation of the TBL1Y protein, a member of the transducin β-like protein family. TBL1Y is encoded by a gene located on the Y chromosome and is implicated in various regulatory functions within the cell, including gene expression modulation and signal transduction pathways. The protein functions as part of a complex that influences the transcriptional machinery, dictating the on or off status of specific genes. Activators of TBL1Y might function by directly binding to the protein, thereby stabilizing its active form or inducing conformational changes that enhance its interaction with other components of the transcriptional regulation complex. Alternatively, these activators may act indirectly by affecting upstream signaling pathways or modifying cofactors that are crucial for TBL1Y activation.
The activation of TBL1Y by these chemicals is of particular interest in research settings, as it allows scientists to probe the functions and regulatory mechanisms of this protein. Through the use of these activators, researchers can investigate the role of TBL1Y in chromatin remodeling and the broader context of epigenetic regulation. Understanding how TBL1Y influences gene expression patterns is pivotal for dissecting the complex network of genetic regulation. Research involving TBL1Y activators typically employs a combination of molecular biology techniques, such as gene reporter assays to monitor changes in transcriptional activity, protein-DNA interaction studies to decipher the direct targets of TBL1Y within the genome, and proteomics approaches to analyze the broader impact of its activation on the cellular proteome.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is a potent and selective histone deacetylase (HDAC) inhibitor. By inhibiting HDACs, it can increase the acetylation of histones, leading to a more open chromatin structure and enhanced transcription of TBL1Y. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a DNA methyltransferase inhibitor. By reducing DNA methylation, it can enhance the expression of TBL1Y by making the gene more accessible for transcription. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
Nicotinamide is a sirtuin inhibitor that can prevent the deacetylation of histones, promoting a more open chromatin structure and potentially enhancing the transcription of TBL1Y. | ||||||
Anacardic Acid | 16611-84-0 | sc-202463 sc-202463A | 5 mg 25 mg | $100.00 $200.00 | 13 | |
Anacardic Acid is a histone acetyltransferase (HAT) activator. By enhancing HAT activity, it can increase the acetylation of histones, leading to enhanced transcription of TBL1Y. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Vorinostat is a potent HDAC inhibitor. By inhibiting HDACs, it can increase the acetylation of histones, leading to enhanced transcription of TBL1Y. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $128.00 $505.00 | 2 | |
RG108 is a DNA methyltransferase inhibitor. It can enhance the expression of TBL1Y by reducing DNA methylation and making the TBL1Y gene more accessible for transcription. | ||||||
Mocetinostat | 726169-73-9 | sc-364539 sc-364539B sc-364539A | 5 mg 10 mg 50 mg | $210.00 $242.00 $1434.00 | 2 | |
Mocetinostat is a potent, selective inhibitor of HDACs. By inhibiting HDACs, it can increase the acetylation of histones, leading to enhanced transcription of TBL1Y. | ||||||
MC 1568 | 852475-26-4 | sc-362767 sc-362767A | 10 mg 50 mg | $179.00 $566.00 | 4 | |
MC1568 is a selective class IIa HDAC inhibitor. It can increase the acetylation of histones, leading to enhanced transcription of TBL1Y. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
Entinostat is a potent HDAC inhibitor. It enhances the acetylation of histones, promoting a more open chromatin structure and potentially enhancing the transcription of TBL1Y. | ||||||
Garcinol | 78824-30-3 | sc-200891 sc-200891A | 10 mg 50 mg | $136.00 $492.00 | 13 | |
Garcinol is a HAT inhibitor. By reducing histone acetylation, it can indirectly enhance the transcription of TBL1Y by altering the balance of acetylation and deacetylation. |