Date published: 2025-10-11

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TBL1Y Activators

TBL1Y activators refer to a diverse group of chemicals that target and promote the activation of the TBL1Y protein, a member of the transducin β-like protein family. TBL1Y is encoded by a gene located on the Y chromosome and is implicated in various regulatory functions within the cell, including gene expression modulation and signal transduction pathways. The protein functions as part of a complex that influences the transcriptional machinery, dictating the on or off status of specific genes. Activators of TBL1Y might function by directly binding to the protein, thereby stabilizing its active form or inducing conformational changes that enhance its interaction with other components of the transcriptional regulation complex. Alternatively, these activators may act indirectly by affecting upstream signaling pathways or modifying cofactors that are crucial for TBL1Y activation.

The activation of TBL1Y by these chemicals is of particular interest in research settings, as it allows scientists to probe the functions and regulatory mechanisms of this protein. Through the use of these activators, researchers can investigate the role of TBL1Y in chromatin remodeling and the broader context of epigenetic regulation. Understanding how TBL1Y influences gene expression patterns is pivotal for dissecting the complex network of genetic regulation. Research involving TBL1Y activators typically employs a combination of molecular biology techniques, such as gene reporter assays to monitor changes in transcriptional activity, protein-DNA interaction studies to decipher the direct targets of TBL1Y within the genome, and proteomics approaches to analyze the broader impact of its activation on the cellular proteome.

Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

Trichostatin A is a potent and selective histone deacetylase (HDAC) inhibitor. By inhibiting HDACs, it can increase the acetylation of histones, leading to a more open chromatin structure and enhanced transcription of TBL1Y.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

5-Azacytidine is a DNA methyltransferase inhibitor. By reducing DNA methylation, it can enhance the expression of TBL1Y by making the gene more accessible for transcription.

Nicotinamide

98-92-0sc-208096
sc-208096A
sc-208096B
sc-208096C
100 g
250 g
1 kg
5 kg
$43.00
$65.00
$200.00
$815.00
6
(1)

Nicotinamide is a sirtuin inhibitor that can prevent the deacetylation of histones, promoting a more open chromatin structure and potentially enhancing the transcription of TBL1Y.

Anacardic Acid

16611-84-0sc-202463
sc-202463A
5 mg
25 mg
$100.00
$200.00
13
(1)

Anacardic Acid is a histone acetyltransferase (HAT) activator. By enhancing HAT activity, it can increase the acetylation of histones, leading to enhanced transcription of TBL1Y.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$130.00
$270.00
37
(2)

Vorinostat is a potent HDAC inhibitor. By inhibiting HDACs, it can increase the acetylation of histones, leading to enhanced transcription of TBL1Y.

RG 108

48208-26-0sc-204235
sc-204235A
10 mg
50 mg
$128.00
$505.00
2
(1)

RG108 is a DNA methyltransferase inhibitor. It can enhance the expression of TBL1Y by reducing DNA methylation and making the TBL1Y gene more accessible for transcription.

Mocetinostat

726169-73-9sc-364539
sc-364539B
sc-364539A
5 mg
10 mg
50 mg
$210.00
$242.00
$1434.00
2
(1)

Mocetinostat is a potent, selective inhibitor of HDACs. By inhibiting HDACs, it can increase the acetylation of histones, leading to enhanced transcription of TBL1Y.

MC 1568

852475-26-4sc-362767
sc-362767A
10 mg
50 mg
$179.00
$566.00
4
(1)

MC1568 is a selective class IIa HDAC inhibitor. It can increase the acetylation of histones, leading to enhanced transcription of TBL1Y.

MS-275

209783-80-2sc-279455
sc-279455A
sc-279455B
1 mg
5 mg
25 mg
$24.00
$88.00
$208.00
24
(2)

Entinostat is a potent HDAC inhibitor. It enhances the acetylation of histones, promoting a more open chromatin structure and potentially enhancing the transcription of TBL1Y.

Garcinol

78824-30-3sc-200891
sc-200891A
10 mg
50 mg
$136.00
$492.00
13
(1)

Garcinol is a HAT inhibitor. By reducing histone acetylation, it can indirectly enhance the transcription of TBL1Y by altering the balance of acetylation and deacetylation.