TACE Activators
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
2-(14,15-Epoxyeicosatrienoyl) Glycerol | 848667-56-1 | sc-205073 sc-205073A | 25 µg 50 µg | $399.00 $748.00 | ||
2-(14,15-Epoxyeicosatrienoyl) Glycerol exhibits intriguing molecular behavior as a trace compound, characterized by its ability to engage in specific lipid interactions. Its unique epoxide structure allows for selective reactivity with nucleophiles, influencing lipid metabolism pathways. The compound's hydrophobic properties enhance membrane integration, potentially altering membrane fluidity and dynamics. Furthermore, its kinetic profile suggests rapid interconversion with other lipid species, impacting cellular signaling cascades. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PKC agonist that activates PKC and induces phosphorylation of ERK1/2 and AP-1 binding to TPA response elements in the TACE promoter. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Glucocorticoid receptor agonist that binds GRE sites in the TACE promoter and activates transcription. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
PPARγ agonist that binds PPRE elements in an enhancer region upstream of TACE to induce its expression. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
DNA damage agent that activates JNK/c-Jun pathway and induces phosphorylation/homodimerization of AP-1 transactivating the TACE promoter. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
HDAC inhibitor that acetylates histones near TACE start site allowing improved accessibility for transcriptional machinery. | ||||||
Arachidonic Acid (20:4, n-6) | 506-32-1 | sc-200770 sc-200770A sc-200770B | 100 mg 1 g 25 g | $90.00 $235.00 $4243.00 | 9 | |
Activates PKC pathway leading to enhanced phosphorylation of Elk1 and increased binding to ETS motifs controlling TACE expression. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
DNA methyltransferase inhibitor preventing methylation marks near TACE and opening chromatin for transcription factor binding. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Anti-inflammatory agent that reduces HDAC1/2 levels permitting greater histone acetylation and TACE expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
SIRT1 activator that may modulate acetylation state of co-regulators of TACE transcription. | ||||||