Syndecan-2 Inhibitors
Syndecan-2 inhibitors are a class of chemical compounds that primarily target the syndecan-2 protein, which is a member of the syndecan family of cell surface proteoglycans. These inhibitors play a crucial role in the field of biomedical research and drug development due to their ability to modulate syndecan-2 function. Syndecan-2 itself is a transmembrane protein found on the surface of various cell types, including epithelial, endothelial, and certain immune cells. It is involved in a range of cellular processes, most notably cell adhesion, signaling, and extracellular matrix interactions. Syndecan-2 is characterized by its unique structure, which includes a core protein that is covalently linked to heparan sulfate chains. These chains are crucial for its ability to interact with various extracellular matrix molecules, growth factors, and cytokines.
The primary function of syndecan-2 inhibitors is to disrupt or modulate the interactions between syndecan-2 and its binding partners. This can be achieved through various mechanisms, such as blocking the heparan sulfate binding sites or interfering with the signaling pathways associated with syndecan-2. By doing so, these inhibitors can influence key cellular processes, including cell migration, adhesion, and proliferation. Researchers often employ syndecan-2 inhibitors as valuable tools to elucidate the role of syndecan-2 in normal physiological processes and disease states.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a catechin found in green tea, known for its antioxidant properties. It may downregulate Syndecan-2 by modulating cellular oxidative stress and signaling pathways. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, found in grapes and red wine, is known for its antioxidative and anti-inflammatory effects. It may decrease Syndecan-2 expression by influencing cellular signaling and gene regulation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, the active component of turmeric, has anti-inflammatory and antioxidative properties. It may inhibit Syndecan-2 by modulating nuclear factor-kB and other signaling pathways. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a flavonoid with antioxidant properties. It may reduce Syndecan-2 expression through its ability to modulate cellular redox status and gene expression. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane is a compound found in cruciferous vegetables. It may downregulate Syndecan-2 expression via its role in detoxification processes and cellular antioxidant defense. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, a soy-derived isoflavone, has been shown to have estrogenic and antioxidant properties. It may influence Syndecan-2 expression through estrogen receptor-mediated pathways. | ||||||
Silybin | 22888-70-6 | sc-202812 sc-202812A sc-202812B sc-202812C | 1 g 5 g 10 g 50 g | $55.00 $114.00 $206.00 $714.00 | 6 | |
Silibinin is a flavonolignan found in milk thistle. It has hepatoprotective and antioxidative properties, potentially influencing Syndecan-2 expression via cellular protective mechanisms. | ||||||
Baicalein | 491-67-8 | sc-200494 sc-200494A sc-200494B sc-200494C | 10 mg 100 mg 500 mg 1 g | $32.00 $42.00 $162.00 $292.00 | 12 | |
Baicalein is a flavone found in the roots of Scutellaria baicalensis. It has anti-inflammatory and antioxidative effects, potentially modulating Syndecan-2 expression. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $27.00 $51.00 $101.00 $153.00 $1925.00 | 40 | |
Luteolin is a flavone with antioxidant and anti-inflammatory properties. It may inhibit Syndecan-2 expression by modulating various signaling pathways and gene expression. | ||||||
(−)Epicatechin | 490-46-0 | sc-205672 sc-205672A | 1 mg 5 mg | $51.00 $138.00 | ||
Epicatechin is a flavanol found in cocoa and green tea. It has antioxidative properties, potentially downregulating Syndecan-2 expression through modulation of cellular redox status. | ||||||