CD362/SDC2/Syndecan-2 Antibody (H-7): sc-365624

Syndecan-2 Antibody (H-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects Syndecan-2 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Syndecan-2 monoclonal antibody (H-7) is specific for an epitope mapping between amino acids 61-81 within an N-terminal extracellular domain of Syndecan-2 of human origin. Anti-Syndecan-2 antibody (H-7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Syndecan-2, also known as fibroglycan or HSPG, plays a crucial role in cell-extracellular matrix interactions and is particularly important in areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and prechondrogenic and preosteogenic mesenchymal condensations. Syndecan-2 is integral to the regulation of cell behavior, influencing processes such as cell adhesion, migration, and proliferation, which are vital for tissue development and repair. Additionally, Syndecan-2 interacts with various growth factors and extracellular matrix components, facilitating signaling pathways essential for embryonic development and tissue homeostasis. Anti-Syndecan-2 antibody (H-7) binding to multiple ligands underscores its significance in cellular communication and maintenance of tissue architecture, making Syndecan-2 a valuable target for research in developmental biology and regenerative medicine.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

CD362/SDC2/Syndecan-2 Antibody (H-7) References:

1. Syndecan-4 signals cooperatively with integrins in a Rho-dependent manner in the assembly of focal adhesions and actin stress fibers.  |  Saoncella, S., et al. 1999. Proc Natl Acad Sci U S A. 96: 2805-10. PMID: 10077592
2. Adhesion of B lymphoid (MPC-11) cells to type I collagen is mediated by integral membrane proteoglycan, syndecan.  |  Sanderson, RD., et al. 1992. J Immunol. 148: 3902-11. PMID: 1602136
3. Syndecan family of cell surface proteoglycans: developmentally regulated receptors for extracellular effector molecules.  |  Salmivirta, M. and Jalkanen, M. 1995. Experientia. 51: 863-72. PMID: 7556568
4. Spatial and temporal changes in the expression of fibroglycan (syndecan-2) during mouse embryonic development.  |  David, G., et al. 1993. Development. 119: 841-54. PMID: 8187643
5. Expression of syndecan-1 and -3 during embryogenesis of the central nervous system in relation to binding with midkine.  |  Nakanishi, T., et al. 1997. J Biochem. 121: 197-205. PMID: 9089390

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-CD362/SDC2/Syndecan-2 Antibody (H-7) has 9 citations in a variety of scientific publications.

Primary antibodies like Anti-CD362/SDC2/Syndecan-2 Antibody (H-7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

CD362/SDC2/Syndecan-2 Antibody (H-7) Specifications

Alternate Product Name: Syndecan-2

Product Clone Name: H-7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 61-81

Epitope Target: Syndecan-2

Epitope Species: human

Product Reactivity/Detection: Syndecan-2

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 9 citations in various scientific publications

Available Conjugates/Forms for CD362/SDC2/Syndecan-2 Antibody (H-7): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin