SUHW1 inhibitors refer to a class of chemical compounds that specifically target and inhibit the activity of the SUHW1 protein, a crucial component involved in various biological processes. SUHW1 is part of a larger family of proteins that play a significant role in regulating gene expression and chromatin structure. By interacting with certain DNA sequences or associated proteins, SUHW1 contributes to controlling how genes are turned on or off. Inhibitors of SUHW1 function by binding to the protein or its active site, thereby disrupting its normal interactions with DNA or chromatin. This inhibition can lead to alterations in the expression of genes regulated by SUHW1, affecting downstream processes such as cell growth, differentiation, or signal transduction.
The specificity of SUHW1 inhibitors arises from their ability to target the structural or functional domains of the protein that are essential for its activity. These inhibitors are designed based on the detailed understanding of the protein's three-dimensional structure and the mechanisms by which it interacts with other molecules. Advanced techniques, such as X-ray crystallography and molecular docking, aid in the rational design of these inhibitors, ensuring that they bind effectively to the protein while minimizing off-target effects. Moreover, the development of SUHW1 inhibitors involves extensive testing to optimize their potency, selectivity, and stability, with researchers studying their effects on various biochemical pathways to better understand the broader implications of SUHW1 inhibition in cellular contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide represses the transcription of certain genes by interfering with transcription factors, potentially reducing SUHW1 expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin alters transcription factor activity and could decrease SUHW1 gene expression by modifying chromatin structure. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG modulates several signaling pathways and transcription factors, which might lead to downregulation of SUHW1 transcription. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol influences gene expression through sirtuin activation, which may result in the downregulation of the SUHW1 gene. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane is known to affect transcription factor NF-kB, potentially decreasing SUHW1 expression indirectly. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
JQ1 inhibits BET bromodomain proteins, which can downregulate transcription, potentially affecting SUHW1 expression. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Decitabine, a DNA methyltransferase inhibitor, can alter gene expression patterns, possibly repressing SUHW1 expression. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Vorinostat inhibits histone deacetylases, leading to chromatin remodeling and possible downregulation of the SUHW1 gene. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A, an HDAC inhibitor, can alter chromatin structure and gene expression, potentially reducing SUHW1 levels. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Sirolimus inhibits mTOR, a pathway that can control protein synthesis and gene expression, potentially reducing SUHW1 levels. | ||||||