SnoN_SnoN2_SnoA Activators
SnoN, SnoN2, and SnoA Activators belong to a class of chemical compounds associated with the modulation or enhancement of the biological activity of proteins from the Sno (Ski novel family) family, including SnoN, SnoN2 (also known as SKIL), and SnoA. These proteins are involved in intricate regulatory networks that control cellular processes such as cell growth, differentiation, and responses to various signaling pathways. Members of the Sno family are characterized by their ability to interact with a range of transcription factors, co-repressors, and co-activators, allowing them to influence gene expression programs.
SnoN, SnoN2, and SnoA Activators are believed to interact with these Sno family proteins, affecting their subcellular localization, stability, or their interactions with other regulatory molecules. By modulating the function of SnoN, SnoN2, and SnoA, these activators can impact downstream gene expression patterns and cellular responses to external cues. Research into SnoN, SnoN2, and SnoA Activators and their effects on Sno family proteins contributes to our understanding of the intricate regulatory mechanisms that govern cell fate decisions, tissue development, and the maintenance of cellular homeostasis. It sheds light on the molecular events underlying processes like epithelial-mesenchymal transition (EMT), cell cycle regulation, and cellular responses to growth factors, all of which are essential for normal cellular function and tissue development.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY2109761 | 700874-71-1 | sc-396262 sc-396262A | 1 mg 5 mg | $89.00 $275.00 | 9 | |
A selective inhibitor of TGF-β receptor type I/II (TβRI/II), indirectly enhancing SnoN activity by reducing TGF-β-mediated degradation of SnoN. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
Inhibits TGF-β type I receptor ALK5, indirectly stabilizing SnoN and promoting its activity in the cell. | ||||||
LY2157299 | 700874-72-2 | sc-391123 sc-391123A | 5 mg 10 mg | $213.00 $359.00 | 3 | |
A selective TGF-β receptor I kinase inhibitor, indirectly promoting SnoN activity by reducing TGF-β signaling. | ||||||
ALK5 Inhibitor II | 446859-33-2 | sc-221234 sc-221234A sc-221234B sc-221234C sc-221234D sc-221234E sc-221234F | 1 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 g | $77.00 $153.00 $219.00 $663.00 $1248.00 $4382.00 $7850.00 | 8 | |
Inhibits ALK5, indirectly enhancing SnoN/SnoN2/SnoA activity by reducing TGF-β-mediated suppression. | ||||||
GW788388 | 452342-67-5 | sc-363544 sc-363544A | 5 mg 25 mg | $95.00 $384.00 | ||
A potent inhibitor of ALK5 and ALK4, stabilizes SnoN by attenuating TGF-β signaling. | ||||||
A 83-01 | 909910-43-6 | sc-203791 sc-203791A | 10 mg 50 mg | $202.00 $811.00 | 16 | |
Selectively inhibits ALK5, ALK4, and ALK7, indirectly enhancing SnoN activity by mitigating TGF-β-induced degradation. | ||||||
TGF-β RI Kinase Inhibitor V | 627536-09-8 | sc-203294 | 2 mg | $88.00 | 3 | |
TGF-β RI Kinase Inhibitor V indirectly upregulates SnoN activity by reducing TGF-β signaling. | ||||||
EW-7197 | 1352608-82-2 | sc-507465 | 5 mg | $345.00 | ||
A selective ALK5 inhibitor, stabilizes SnoN proteins by diminishing TGF-β pathway activation. | ||||||
LY 364947 | 396129-53-6 | sc-203122 sc-203122A | 5 mg 10 mg | $107.00 $156.00 | 4 | |
Hinders TGF-β receptor I kinase, indirectly enhancing SnoN function by limiting TGF-β-mediated effects. | ||||||
TGF-β RI Kinase Inhibitor VIII | 356559-20-1 | sc-203295 | 2 mg | $100.00 | 2 | |
Selectively inhibits ALK5, indirectly promoting SnoN activity by reducing its degradation via TGF-β signaling. | ||||||