SnoN_SnoN2_SnoA Inhibitors
SnoN inhibitors belong to a class of small molecules or compounds designed to target the protein SnoN, which plays a critical role in various cellular processes, particularly in the regulation of gene expression and cell growth. SnoN, short for Ski-related novel gene, is a transcriptional co-repressor that can interact with several key regulatory proteins, including transcription factors like Smad proteins and histone deacetylases (HDACs). The primary function of SnoN is to suppress the transcription of specific genes, acting as a negative regulator of various signaling pathways. When SnoN is overexpressed or dysregulated, it can contribute to the development of several diseases.
SnoN inhibitors are designed to interfere with the activity of SnoN, typically by binding to it and preventing its interactions with other proteins or DNA. By inhibiting SnoN, these compounds aim to modulate the transcription of target genes and influence various cellular processes. This class of inhibitors represents a promising avenue for research into understanding the underlying molecular mechanisms of diseases associated with SnoN dysregulation. Researchers are actively investigating SnoN inhibitors to uncover applications and gain insights into the roles SnoN plays in normal cellular physiology and pathology. These inhibitors elucidate the intricate regulatory networks within cells and may ultimately lead to novel approaches for addressing diseases linked to SnoN dysfunction.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits the mTOR pathway, which has been shown to downregulate SnoN expression. This reduction in SnoN may result from altered cellular signaling and changes in transcriptional regulation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin downregulates the expression of various proteins through its anti-inflammatory and antioxidant properties. It may influence SnoN expression indirectly by modulating signaling pathways and transcription factors. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol is a polyphenolic compound known to modulate multiple signaling pathways. It may decrease SnoN expression as part of its broader effects on cell cycle regulation and response to oxidative stress. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin influences various signaling pathways and has antioxidant properties. Its potential to inhibit SnoN expression may be related to these broad cellular effects, impacting transcription and protein stability. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein is an isoflavone with potential to alter cell signaling and gene expression. It may influence SnoN levels through its effects on estrogen receptors and related signaling pathways. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
DL-Sulforaphane has been shown to modify gene expression and exert anti-inflammatory effects. Its potential to inhibit SnoN expression may stem from these activities, impacting cellular signaling and protein synthesis. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
(-)-Epigallocatechin Gallate, a major component of green tea, has numerous effects on cell signaling and gene expression. It may reduce SnoN levels as part of its broader effects on cellular function, including anti-inflammatory and antioxidant activities. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $57.00 $93.00 $240.00 $713.00 | 8 | |
Ellagic acid is a polyphenol with potential anti-inflammatory and antioxidant properties. It may downregulate SnoN expression by influencing cellular signaling pathways and modulating transcriptional activity. | ||||||
Silybin | 22888-70-6 | sc-202812 sc-202812A sc-202812B sc-202812C | 1 g 5 g 10 g 50 g | $54.00 $112.00 $202.00 $700.00 | 6 | |
Silybin has shown potential to modulate gene expression and cell signaling. It may impact SnoN levels as part of its broader effects on cellular function, including anti-inflammatory and antioxidant roles. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $90.00 | 1 | |
Berberine is an alkaloid with diverse effects on cell signaling and gene expression. It may reduce SnoN expression through its influence on various signaling pathways and transcriptional regulators. | ||||||