SNAT2 Inhibitors
SNAT2 inhibitors are a class of chemical compounds that target the Sodium-coupled neutral amino acid transporter 2 (SNAT2), a critical protein involved in the transport of amino acids across cell membranes. These inhibitors belong to the broader category of transporter inhibitors, which are designed to modulate the activity of specific transport proteins in cells. SNAT2, also known as SLC38A2, is primarily found in the plasma membrane of various cell types, where it plays a crucial role in the uptake of essential neutral amino acids such as glutamine, alanine, and proline. These amino acids are fundamental building blocks for protein synthesis, energy production, and various metabolic processes within the cell.
SNAT2 inhibitors work by binding to SNAT2 and interfering with its function, preventing the uptake of specific amino acids into the cell. By doing so, they can disrupt the normal flow of amino acids and consequently affect the cell's metabolic and physiological processes that rely on these molecules. The development and study of SNAT2 inhibitors have gained attention in the field of research due to their implications in understanding amino acid transport, cellular metabolism, and their roles in various diseases. Researchers are exploring the use of SNAT2 inhibitors as tools to probe amino acid transport mechanisms and to investigate the impact of amino acid dysregulation on cell function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is a known mTOR inhibitor that can downregulate protein synthesis and may influence the expression of transporters like SNAT2 as part of its role in cellular growth and metabolism regulation. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
As a glucocorticoid, Dexamethasone can modulate gene expression. It may downregulate SNAT2 expression as part of its wide range of effects on cellular processes. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $42.00 $62.00 $153.00 $255.00 $500.00 $30.00 | 37 | |
1,1-Dimethylbiguanide, Hydrochloride is known to influence cellular metabolism and has been shown to interact with mTOR pathways, potentially leading to decreased SNAT2 expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin, a bioactive compound from turmeric, has anti-inflammatory properties and can modulate various signaling pathways, potentially leading to reduced SNAT2 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, found in grapes and red wine, is known to have antioxidant properties and can modulate signaling pathways, possibly influencing SNAT2 expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
As a flavonoid with antioxidant properties, Quercetin can modulate various cellular processes and potentially downregulate the expression of proteins like SNAT2. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Found in green tea, this compound has antioxidant properties and has been shown to influence various cellular pathways, potentially leading to decreased expression of SNAT2. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
DL-Sulforaphane, found in cruciferous vegetables, has been shown to modulate gene expression and could potentially downregulate SNAT2 expression as part of its cellular effects. | ||||||
Salicylic acid | 69-72-7 | sc-203374 sc-203374A sc-203374B | 100 g 500 g 1 kg | $46.00 $92.00 $117.00 | 3 | |
Salicylic Acid has anti-inflammatory properties and can modulate various cellular processes. It may have the potential to influence the expression of proteins like SNAT2. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic Acid, a metabolite of vitamin A, plays a crucial role in cell growth and differentiation, potentially leading to modulation of transporter protein expression, including SNAT2. | ||||||