Date published: 2025-10-8

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SIRT1 Antibodies

Santa Cruz Biotechnology features a diverse variety of SIRT1 monoclonal antibodies for various research applications. SIRT1 Antibodies are optimized for techniques such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). SIRT1, or Sirtuin 1, is a NAD+-dependent deacetylase that plays a crucial role in cellular regulation, influencing processes such as aging, metabolism, and stress response. Through modulation of protein acetylation status, SIRT1 regulates gene expression, DNA repair, and apoptosis, making it a significant target in studies related to cancer, neurodegenerative diseases, and metabolic disorders. Understanding SIRT1 function is essential for advancing therapeutic strategies in these areas. SIRT1 research has revealed its importance in maintaining cellular homeostasis and its potential as a therapeutic target. Recent studies have highlighted SIRT1's role in neuroprotection and metabolic regulation. Ongoing research continues to uncover new functions and regulatory mechanisms of SIRT1 in various biological processes. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing SIRT1-related discoveries and therapeutic developments.

SEE ALSO...

SIRT1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SIRT1 Antibody (B-7)

sc-74465mouse IgG1 κ448-747 (h)WB, IP, IF, IHC(P), ELISAm, r, h
174
(35)

SIRT1 Antibody (B-10)

sc-74504mouse IgG2b κ448-747 (h)WB, IP, IF, IHC(P), ELISAh
99
(43)

SIRT1 Antibody (33.36)

sc-135792mouse IgG1 κ(h)WB, IP, IF, IHC(P), ELISAm, r, h
9
(2)

SIRT1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SIRT1 CRISPR/Cas9 KO Plasmid (h)

sc-400085hGene KnockoutGFP
7
(4)

SIRT1 HDR Plasmid (h)

sc-400085-HDRhHomology Directed RepairPuromycin
7
(4)

SIRT1 Double Nickase Plasmid (h)

sc-400085-NIChGene KnockoutPuromycin
7
(4)

SIRT1 Double Nickase Plasmid (h2)

sc-400085-NIC-2hGene KnockoutPuromycin
7
(4)

SIRT1 CRISPR/Cas9 KO Plasmid (m2)

sc-430046-KO-2mGene KnockoutGFP0
(0)

SIRT1 HDR Plasmid (m2)

sc-430046-HDR-2mHomology Directed RepairPuromycin0
(0)

SIRT1 Double Nickase Plasmid (m)

sc-430046-NICmGene KnockoutPuromycin0
(0)

SIRT1 Double Nickase Plasmid (m2)

sc-430046-NIC-2mGene KnockoutPuromycin0
(0)

SIRT1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SIRT1 CRISPR Activation Plasmid (h)

sc-400085-ACThGene ActivationPuro, Blast, Hygro
7
(4)

SIRT1 CRISPR Activation Plasmid (h2)

sc-400085-ACT-2hGene ActivationPuro, Blast, Hygro
7
(4)

SIRT1 Lentiviral Activation Particles (h)

sc-400085-LAChGene ActivationPuro, Blast, Hygro
7
(4)

SIRT1 Lentiviral Activation Particles (h2)

sc-400085-LAC-2hGene ActivationPuro, Blast, Hygro
7
(4)

SIRT1 CRISPR Activation Plasmid (m)

sc-430046-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SIRT1 CRISPR Activation Plasmid (m2)

sc-430046-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SIRT1 Lentiviral Activation Particles (m)

sc-430046-LACmGene ActivationPuro, Blast, Hygro0
(0)

SIRT1 Lentiviral Activation Particles (m2)

sc-430046-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SIRT1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SIRT1 siRNA (h)

sc-40986hGene SilencingN/A
124
(1)

SIRT1 shRNA Plasmid (h)

sc-40986-SHhGene SilencingPuromycin
124
(1)

SIRT1 shRNA (h) Lentiviral Particles

sc-40986-VhGene SilencingPuromycin
124
(1)

SIRT1 siRNA (m)

sc-40987mGene SilencingN/A
55
(0)

SIRT1 shRNA Plasmid (m)

sc-40987-SHmGene SilencingPuromycin
55
(0)

SIRT1 shRNA (m) Lentiviral Particles

sc-40987-VmGene SilencingPuromycin
55
(0)

SIRT1 siRNA (r)

sc-108043rGene SilencingN/A
45
(0)

SIRT1 shRNA Plasmid (r)

sc-108043-SHrGene SilencingPuromycin
45
(0)

SIRT1 shRNA (r) Lentiviral Particles

sc-108043-VrGene SilencingPuromycin
45
(0)