Date published: 2026-6-8

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SIRT6 Antibodies

Santa Cruz Biotechnology offers a broad range of SIRT6 monoclonal antibodies for investigating SIRT6 in cellular processes. SIRT6 Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). SIRT6 is a member of the sirtuin family, which regulates cellular metabolism, DNA repair, and aging processes. SIRT6 maintains genomic stability through its involvement in DNA repair mechanisms and chromatin remodeling. Research has shown SIRT6's crucial role in regulating inflammation responses throughout the body. SIRT6 also participates in glucose homeostasis, making it particularly relevant for metabolic research. Understanding SIRT6 function has significant implications for age-related diseases and cancer development. Current research continues to uncover new roles for SIRT6 in cellular pathways and disease mechanisms. SIRT6 has emerged as a promising target for therapeutic interventions in multiple disorders. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of SIRT6's role in health and disease.

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SIRT6 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SIRT6 Antibody (2G1H1)

sc-517196mouse IgG1 κ141-250 (h)WB, IP, IF, ELISAh
16
(7)

SIRT6 Antibody (6C9-D10-D3)

sc-517556mouse IgG(h)WB, IF, IHC(P)m, r, h
4
(0)

SIRT6 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SIRT6 CRISPR/Cas9 KO Plasmid (h)

sc-412216hGene KnockoutGFP0
(1)

SIRT6 HDR Plasmid (h)

sc-412216-HDRhHomology Directed RepairPuromycin0
(1)

SIRT6 Double Nickase Plasmid (h)

sc-412216-NIChGene KnockoutPuromycin0
(1)

SIRT6 Double Nickase Plasmid (h2)

sc-412216-NIC-2hGene KnockoutPuromycin0
(1)

SIRT6 CRISPR/Cas9 KO Plasmid (m2)

sc-424467-KO-2mGene KnockoutGFP
1
(0)

SIRT6 HDR Plasmid (m2)

sc-424467-HDR-2mHomology Directed RepairPuromycin
1
(0)

SIRT6 Double Nickase Plasmid (m)

sc-424467-NICmGene KnockoutPuromycin
1
(0)

SIRT6 Double Nickase Plasmid (m2)

sc-424467-NIC-2mGene KnockoutPuromycin
1
(0)

SIRT6 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SIRT6 CRISPR Activation Plasmid (m)

sc-424467-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

SIRT6 CRISPR Activation Plasmid (m2)

sc-424467-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

SIRT6 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SIRT6 siRNA (h)

sc-63028hGene SilencingN/A
13
(0)

SIRT6 shRNA Plasmid (h)

sc-63028-SHhGene SilencingPuromycin
13
(0)

SIRT6 shRNA (h) Lentiviral Particles

sc-63028-VhGene SilencingPuromycin
13
(0)

SIRT6 siRNA (m)

sc-63029mGene SilencingN/A
4
(0)

SIRT6 shRNA Plasmid (m)

sc-63029-SHmGene SilencingPuromycin
4
(0)

SIRT6 shRNA (m) Lentiviral Particles

sc-63029-VmGene SilencingPuromycin
4
(0)