Septin 7 Inhibitors
Septin 7 inhibitors belong to a class of small molecules that are designed to target and modulate the activity of Septin 7, a critical protein involved in cell division and cellular organization. Septins are a family of GTP-binding proteins that play essential roles in various cellular processes, including cytokinesis, cell polarity, and membrane remodeling. Among these septins, Septin 7 stands out as a pivotal player in forming higher-order septin structures, acting as a scaffold to organize other septin subunits. Inhibitors of Septin 7 have gained attention in the field of cell biology and molecular research due to their ability to disrupt septin-based structures, thereby providing valuable insights into the fundamental mechanisms governing cell division and intracellular organization.
The development of Septin 7 inhibitors has been driven by the desire to understand the intricate roles that septins play in cellular processes. By selectively targeting Septin 7, these inhibitors can interfere with the assembly of septin filaments and disrupt the organization of cellular structures such as the cytokinetic ring, leading to aberrant cell division. Researchers utilize Septin 7 inhibitors as powerful tools to dissect the functions of septins and their implications for cell biology. Furthermore, these compounds have shown promise in elucidating the connections between septins and various diseases, including cancer and neurodegenerative disorders. Overall, Septin 7 inhibitors represent a valuable class of molecules that have advanced our understanding of cell biology and have the ability to uncover novel insights into disease mechanisms.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is a macrolide compound that inhibits mTOR (mechanistic target of rapamycin), a key regulator of cell growth and proliferation. By modulating mTOR activity, Rapamycin may indirectly impact the expression of Septin 7. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a potent inhibitor of protein kinases. Given the involvement of protein kinases in regulating gene expression and protein stability, Staurosporine could influence Septin 7 expression through modulation of these pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a specific inhibitor of PI3K (phosphoinositide 3-kinase), which is involved in numerous cellular processes including cell growth, proliferation, and survival. Inhibition of PI3K could lead to changes in Septin 7 expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin is a natural compound found in turmeric, with anti-inflammatory and antioxidant properties. It modulates various signaling pathways, and could potentially influence the expression of Septin 7. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol is a polyphenolic compound found in grapes and red wine. It has been shown to modulate multiple cellular processes and signaling pathways, which could lead to changes in Septin 7 expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin is a flavonoid with antioxidant properties. It modulates various signaling pathways and has been shown to influence gene expression, potentially affecting Septin 7 levels. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane is a compound found in cruciferous vegetables. It is known to modulate various signaling pathways and transcription factors, potentially leading to changes in the expression of Septin 7. | ||||||
Autophagy Inhibitor, 3-MA | 5142-23-4 | sc-205596 sc-205596A | 50 mg 500 mg | $56.00 $256.00 | 113 | |
3-MA is a known autophagy inhibitor that specifically inhibits Class III PI3-kinase. Given the role of autophagy in cellular homeostasis and protein turnover, inhibition of this pathway could impact Septin 7 expression. | ||||||
Salicylic acid | 69-72-7 | sc-203374 sc-203374A sc-203374B | 100 g 500 g 1 kg | $46.00 $92.00 $117.00 | 3 | |
Salicylic acid, a derivative of salicylic acid, has anti-inflammatory properties and can modulate various signaling pathways. Its effects on cellular processes could lead to changes in the expression of Septin 7. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG is the most abundant catechin in tea and has various biological effects. It modulates numerous signaling pathways and has been shown to influence gene expression, potentially affecting Septin 7 levels. | ||||||