Septin 7 Activators
Septin 7 activators belong to a class of chemical compounds designed to interact with and modulate the activity of the Septin 7 protein, a member of the septin family. Septins are a group of conserved GTP-binding proteins that are integral to various cellular processes, including cell division, cytoskeletal organization, membrane dynamics, and cell polarity. Septin 7, in particular, is recognized for its role in regulating the assembly and stability of septin filaments, which are essential for the proper functioning of cells and tissues. Activators targeting Septin 7 aim to influence its biochemical properties and interactions, thereby modulating the assembly and function of septin complexes.
The mechanism of action of Septin 7 activators typically involves their binding to specific regions of the Septin 7 protein, often at sites that are critical for GTP binding or septin polymerization. By doing so, these compounds can influence the nucleotide-bound state of Septin 7 and its ability to form higher-order septin structures. This modulation may lead to alterations in the organization of septin filaments and their involvement in various cellular processes. Researchers are actively exploring the molecular details of Septin 7 activation and its downstream effects to gain a deeper understanding of septin biology and its impact on cellular functions. These studies contribute to our knowledge of fundamental cell biology and have the ability to uncover new insights into cell division, cytoskeletal dynamics, and other essential cellular processes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin directly activates adenylate cyclase, leading to increased cAMP levels which can indirectly influence Septin 7 by modulating cAMP-dependent pathways. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $126.00 $328.00 | 30 | |
8-Bromo-cAMP is a cAMP analog that activates cAMP-dependent pathways, potentially affecting Septin 7 activity indirectly. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX is a non-selective inhibitor of phosphodiesterases, which increases intracellular cAMP levels, thereby potentially affecting Septin 7 activity. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632 is a ROCK inhibitor, which can influence Septin 7 by altering actin cytoskeleton dynamics. | ||||||
Thymosin β4 | 77591-33-4 | sc-396076 sc-396076A | 1 mg 100 mg | $134.00 $7140.00 | ||
Thymosin β4 modulates actin polymerization, potentially influencing Septin 7 through cytoskeletal changes. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
Jasplakinolide stabilizes actin filaments, which can affect Septin 7 activity indirectly by altering the cytoskeleton. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Cytochalasin D disrupts actin filaments, indirectly affecting Septin 7 function by modifying the cytoskeleton. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $91.00 $267.00 | 13 | |
ML-7 hydrochloride is an inhibitor of myosin light chain kinase, which can influence Septin 7 activity through effects on the actin cytoskeleton. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C, which can indirectly influence Septin 7 through various signaling pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a PI3K inhibitor, which can affect Septin 7 activity indirectly by altering downstream signaling pathways. | ||||||