Date published: 2026-3-31

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scc-112_Pds5a Inhibitors

The class of chemical compounds known as scc-112_Pds5a inhibitors is a specialized group of molecules designed to interact with and modulate the activity of the scc-112 protein complex, which includes Pds5a as one of its essential components. Scc-112 is a crucial player in various cellular processes, particularly in the context of chromosome organization, condensation, and segregation during cell division. Pds5a, as a component of this complex, is involved in mediating the cohesion and proper alignment of sister chromatids, ensuring the accurate distribution of genetic material to daughter cells. Inhibitors targeting scc-112_Pds5a aim to either disrupt the formation or function of this protein complex or modulate its activity, thus influencing chromosomal dynamics and cell division processes.

The development and study of scc-112_Pds5a inhibitors are rooted in the fundamental understanding of cell cycle regulation and genomic stability. Proper chromosome segregation is essential for the maintenance of genetic integrity, and any dysregulation in this process can lead to various cellular abnormalities, including aneuploidy and genomic instability. These inhibitors offer a means to probe the intricate molecular mechanisms involved in chromosome cohesion and segregation, allowing researchers to gain insights into cell cycle regulation and the maintenance of genomic fidelity. Investigations into scc-112_Pds5a inhibitors may provide valuable contributions to the broader field of cell biology, shedding light on the molecular underpinnings of chromosome dynamics, which are crucial for normal cellular function and development.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

This cytidine analog can incorporate into DNA and impact gene expression, potentially affecting PDS5A expression.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

As a histone deacetylase inhibitor, it can influence chromatin structure and might indirectly affect cohesin function.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$133.00
$275.00
37
(2)

Another histone deacetylase inhibitor that can alter chromatin structure and subsequently cohesin's chromatin association.

Olaparib

763113-22-0sc-302017
sc-302017A
sc-302017B
250 mg
500 mg
1 g
$210.00
$305.00
$495.00
10
(1)

PARP inhibitor that affects DNA repair pathways. Given cohesin's role in DNA repair, this could influence cohesin-associated proteins like PDS5A.

Cisplatin

15663-27-1sc-200896
sc-200896A
100 mg
500 mg
$138.00
$380.00
101
(4)

DNA cross-linking agent that can disturb DNA structure and potentially influence cohesin-associated functions.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$58.00
$186.00
$94.00
21
(2)

Inhibits DNA topoisomerase I, potentially affecting DNA structure and indirectly impacting cohesin functions.

Etoposide (VP-16)

33419-42-0sc-3512B
sc-3512
sc-3512A
10 mg
100 mg
500 mg
$51.00
$231.00
$523.00
63
(1)

Inhibits DNA topoisomerase II, which might influence chromatin structure and cohesin's chromatin association.

L-Mimosine

500-44-7sc-201536A
sc-201536B
sc-201536
sc-201536C
25 mg
100 mg
500 mg
1 g
$36.00
$88.00
$220.00
$436.00
8
(2)

Inhibits DNA synthesis, potentially affecting chromosome structure and cohesin-associated processes.

Aphidicolin

38966-21-1sc-201535
sc-201535A
sc-201535B
1 mg
5 mg
25 mg
$84.00
$306.00
$1104.00
30
(3)

DNA polymerase inhibitor which might disturb DNA synthesis and indirectly influence cohesin's functions.

Daunorubicin hydrochloride

23541-50-6sc-200921
sc-200921A
sc-200921B
sc-200921C
10 mg
50 mg
250 mg
1 g
$105.00
$438.00
$837.00
$1569.00
4
(1)

Intercalates into DNA, potentially affecting chromatin structure and cohesin's role in chromosomal processes.