RP23-98M14.2 Inhibitors
RP23-98M14.2 inhibitors represent a chemically distinct class of compounds designed to target a specific molecular site, often involving enzyme-substrate interactions or receptor-ligand binding dynamics. These inhibitors function primarily through reversible or irreversible interactions with their biological targets, blocking or modulating key processes such as signal transduction or metabolic pathways. Structurally, RP23-98M14.2 inhibitors are known for their unique scaffold, which allows for selective binding to their target sites, often via hydrogen bonding, hydrophobic interactions, or electrostatic forces. The structural framework typically consists of a core moiety that may include heterocyclic rings, aromatic groups, or aliphatic chains, providing versatility in molecular binding properties. Their binding dynamics are largely determined by the nature of their active site interactions, which often involve critical residues within the target protein or receptor, enhancing specificity and reducing off-target effects.
In terms of chemical reactivity, RP23-98M14.2 inhibitors exhibit properties that can be finely tuned through synthetic modifications to enhance binding affinity, solubility, or stability. Functional groups such as amides, sulfonamides, or halogens may be incorporated into the molecular backbone to modulate electron density or steric effects, which in turn influences how the inhibitor interacts with its target. Many RP23-98M14.2 inhibitors also demonstrate a degree of conformational flexibility, which is essential for adapting to the three-dimensional shape of their binding site. The study of these inhibitors includes an emphasis on structure-activity relationships (SAR), where slight modifications to the chemical structure can drastically affect inhibitory potency, making these molecules a key subject of interest for further chemical exploration and mechanistic study.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein is a tyrosine kinase inhibitor that can interfere with the phosphorylation of proteins. If RP23-98M14.2 relies on phosphorylation for its activity, genistein would reduce its functional activity by preventing this post-translational modification. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor that blocks the PI3K/Akt signaling pathway. If RP23-98M14.2 is regulated by or involved in this pathway, inhibition of PI3K would lead to decreased activity of RP23-98M14.2 by reducing the pathway's downstream signaling events. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin selectively inhibits mTOR by binding to its intracellular receptor, FKBP12. If RP23-98M14.2 activity is mTOR-dependent, rapamycin would lead to functional inhibition of RP23-98M14.2 by disrupting mTOR-mediated signaling. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a selective inhibitor of MEK, which acts upstream of MAPK/ERK. Inhibition of MEK would lead to decreased ERK phosphorylation and activity. If RP23-98M14.2 operates within the MAPK/ERK pathway, its activity would be indirectly diminished by PD98059. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor. If RP23-98M14.2 is a downstream target of p38 MAPK or is involved in cellular responses mediated by p38 MAPK, its inhibition by SB203580 would result in a decrease in the functional activity of RP23-98M14.2. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is a MEK1/2 inhibitor and by inhibiting MEK1/2, U0126 impairs the activation of the ERK1/2 MAPKs. Should RP23-98M14.2 be implicated in this signaling pathway, its inhibition by U0126 would result in reduced RP23-98M14.2 function. | ||||||
NF 449 | 389142-38-5 | sc-203159 | 10 mg | $308.00 | 5 | |
NF449 is a potent and selective inhibitor of Gs-alpha subunit of G-protein. If RP23-98M14.2 is activated by G-protein-coupled receptor signaling via the Gs-alpha subunit, NF449 would lead to a decrease in RP23-98M14.2 activation by obstructing this signaling route. | ||||||
W-7 | 61714-27-0 | sc-201501 sc-201501A sc-201501B | 50 mg 100 mg 1 g | $163.00 $300.00 $1642.00 | 18 | |
W-7 Hydrochloride is a calmodulin antagonist that inhibits calcium-calmodulin-dependent processes. If the activity of RP23-98M14.2 is calmodulin-dependent, inhibition of calmodulin by W-7 would lead to decreased activity of RP23-98M14.2. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $103.00 $293.00 $465.00 | 15 | |
Go 6983 is a pan-PKC inhibitor. If RP23-98M14.2 is modulated by protein kinase C (PKC) isoforms, Go 6983 would lead to its functional downregulation by inhibiting PKC activity which is necessary for RP23-98M14.2 activation. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of c-Jun N-terminal kinase (JNK). If RP23-98M14.2 functions downstream of JNK signaling or if JNK activity modulates RP23-98M14.2, then SP600125 would indirectly decrease the activity of RP23-98M14.2 by blocking JNK. | ||||||