Date published: 2026-5-30

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RES4-22 Activators

RES4-22 activators belong to a specialized class of chemical compounds that are designed to influence specific biological pathways by modulating the activity of a particular subset of proteins or receptors within the cell. The term "RES4-22" is indicative of a targeted mechanism of action, where "RES" could refer to a specific receptor or regulatory element within the cellular machinery, and "22" may denote the particular subtype or version of this element that is the focus of activation. These activators are typically the result of extensive research into the molecular biology of cells, including the intricate network of signaling pathways that govern cellular function and the regulation of gene expression. The precise structure of these molecules is often complex, featuring a variety of functional groups that allow for selective interaction with their target, which confers a high degree of specificity and reduces the likelihood of off-target effects.

The development of RES4-22 activators is a sophisticated process that involves a deep understanding of chemistry and cell biology. These compounds are usually synthesized through a series of organic reactions, each step meticulously designed to add specific atoms or groups to the growing molecule, shaping its three-dimensional structure and chemical properties. The architecture of RES4-22 activators is critical: it must allow the compound to cross cellular membranes, resist metabolic degradation, and engage with the target site effectively. Such activators often mimic or enhance the action of naturally occurring ligands-molecules that bind to receptors-thereby modulating signaling pathways in a very precise fashion. The binding of these activators to their targets leads to a conformational change that triggers a cascade of intracellular events. This cascade results in the upregulation of the activity of a particular protein or group of proteins, culminating in the modulation of cellular functions that are governed by the pathway in which the target is involved. The design of RES4-22 activators is a testament to the power of modern chemistry and molecular biology to manipulate complex biological systems at a very fundamental level.

SEE ALSO...

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin activates adenylate cyclase, leading to an increase in cyclic AMP (cAMP) levels. Elevated cAMP activates protein kinase A (PKA), which can then phosphorylate and enhance the activity of RES4-22 by altering its conformation or interaction with other cellular components.

Ionomycin

56092-82-1sc-3592
sc-3592A
1 mg
5 mg
$78.00
$270.00
80
(4)

Ionomycin is a calcium ionophore that increases intracellular calcium levels. This rise in calcium can activate calcium-dependent protein kinases, which may then phosphorylate RES4-22, thereby enhancing its activity.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

PMA is an activator of protein kinase C (PKC). PKC can phosphorylate RES4-22 directly or can modulate other signaling pathways that converge on the activation of RES4-22.

Isoproterenol Hydrochloride

51-30-9sc-202188
sc-202188A
100 mg
500 mg
$28.00
$38.00
5
(0)

Isoproterenol is a beta-adrenergic agonist that activates adenylate cyclase, increasing cAMP levels and thereby activating PKA. PKA then has the potential to enhance RES4-22 activity through phosphorylation.

Okadaic Acid

78111-17-8sc-3513
sc-3513A
sc-3513B
25 µg
100 µg
1 mg
$291.00
$530.00
$1800.00
78
(4)

Okadaic Acid is a potent inhibitor of protein phosphatases 1 and 2A, leading to an increase in phosphorylation levels of proteins within the cell. This can result in the enhanced phosphorylation and activation of RES4-22.

Dibutyryl-cAMP

16980-89-5sc-201567
sc-201567A
sc-201567B
sc-201567C
20 mg
100 mg
500 mg
10 g
$47.00
$136.00
$492.00
$4552.00
74
(7)

Dibutyryl-cAMP is a cell-permeable cAMP analog that directly activates PKA. Activation of PKA can lead to enhanced activity of RES4-22 through phosphorylation.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$99.00
$259.00
36
(2)

Anisomycin is an activator of the Stress-Activated Protein Kinases (SAPKs)/Jun amino-terminal kinases (JNKs). Activation of these kinases can lead to phosphorylation of transcription factors that enhance the expression of RES4-22.

Bryostatin 1

83314-01-6sc-201407
10 µg
$245.00
9
(1)

Bryostatin 1 is an activator of PKC, and by activating PKC, it can enhance the phosphorylation and thus the activity of RES4-22.

Calyculin A

101932-71-2sc-24000
sc-24000A
10 µg
100 µg
$163.00
$800.00
59
(3)

Calyculin A is an inhibitor of protein phosphatases 1 and 2A, similar to okadaic acid; it maintains proteins in a phosphorylated state, potentially enhancing the activity of RES4-22 through increased phosphorylation.

8-Bromo-cAMP

76939-46-3sc-201564
sc-201564A
10 mg
50 mg
$126.00
$328.00
30
(1)

8-Bromo-cAMP is a cell-permeable cAMP analog that activates PKA, leading to enhanced phosphorylation and activity of RES4-22.