REP-1 Activators
The chemical class of REP-1 Activators includes a range of compounds that could potentially influence the activity of REP-1, also known as Choroideremia protein, indirectly. REP-1 is crucial in the intracellular trafficking and function of Rab proteins, which are key regulators of vesicle transport in cells. The modulation of REP-1 activity is closely linked to various cellular signaling pathways and processes that govern intracellular trafficking and vesicle dynamics.
Compounds such as Forskolin, which increases cAMP levels, and Phorbol 12-myristate 13-acetate (PMA), an activator of protein kinase C, demonstrate their potential to influence REP-1 activity through their modulation of specific signaling pathways. Forskolin's role in elevating cAMP levels and PMA's activation of PKC highlight the complex interplay between cellular signaling and the regulation of vesicle trafficking. Similarly, growth factors like Epidermal Growth Factor (EGF) and signaling molecules such as Retinoic Acid could also play a role in modulating REP-1 activity through their effects on cell proliferation and differentiation.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Increases cAMP levels, potentially influencing REP-1 activity through cAMP-dependent pathways. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Involved in cell differentiation and growth, could indirectly affect REP-1 activity. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates protein kinase C (PKC), potentially affecting REP-1 activity indirectly through PKC-mediated signaling. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, might influence REP-1 activity indirectly through mTOR signaling pathways. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Inhibits GSK-3β, potentially affecting REP-1 through Wnt signaling pathways. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
Modulates oxidative stress, potentially affecting REP-1 through redox balance pathways. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $42.00 $62.00 $153.00 $255.00 $500.00 $30.00 | 37 | |
Influences AMPK signaling, potentially affecting REP-1 activity through metabolic pathways. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Influences various signaling pathways, potentially modulating REP-1 activity. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
A glucocorticoid, might influence REP-1 activity through glucocorticoid signaling pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor, could affect REP-1 indirectly through the PI3K-Akt pathway. | ||||||